Literature DB >> 21626963

Water equivalent path length measurement in proton radiotherapy using time resolved diode dosimetry.

B Gottschalk1, S Tang, E H Bentefour, E W Cascio, D Prieels, H M Lu.   

Abstract

PURPOSE: To verify water equivalent path length (WEPL) before treatment in proton radiotherapy using time resolved in vivo diode dosimetry.
METHODS: Using a passively scattered range modulated proton beam, the output of a diode driving a fast current-to-voltage amplifier is recorded at a number of depths in a water tank. At each depth, a burst of overlapping single proton pulses is observed. The rms duration of the burst is computed and the resulting data set is fitted with a cubic polynomial.
RESULTS: When the diode is subsequently set to an arbitrary depth and the polynomial is used as a calibration curve, the "unknown" depth is determined within 0.3 mm rms.
CONCLUSIONS: A diode or a diode array, placed (for instance) in the rectum in conjunction with a rectal balloon, can potentially determine the WEPL at that point, just prior to treatment, with submillimeter accuracy, allowing the beam energy to be adjusted. The associated unwanted dose is about 0.2% of a typical single fraction treatment dose.

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Year:  2011        PMID: 21626963      PMCID: PMC3081869          DOI: 10.1118/1.3567498

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

1.  Optimization of current modulation function for proton spread-out Bragg peak fields.

Authors:  Hsiao-Ming Lu; Hanne Kooy
Journal:  Med Phys       Date:  2006-05       Impact factor: 4.071

2.  A potential method for in vivo range verification in proton therapy treatment.

Authors:  Hsiao-Ming Lu
Journal:  Phys Med Biol       Date:  2008-02-19       Impact factor: 3.609

3.  Dosimetry of proton beams using small silicon diodes.

Authors:  A M Koehler
Journal:  Radiat Res Suppl       Date:  1967
  3 in total
  5 in total

1.  Validation of an in-vivo proton beam range check method in an anthropomorphic pelvic phantom using dose measurements.

Authors:  El H Bentefour; Shikui Tang; Ethan W Cascio; Mauro Testa; Deepak Samuel; Damien Prieels; Bernard Gottschalk; Hsiao-Ming Lu
Journal:  Med Phys       Date:  2015-04       Impact factor: 4.071

2.  A novel proton-integrating radiography system design using a monolithic scintillator detector: experimental studies.

Authors:  Chinmay D Darne; Daniel G Robertson; Fahed Alsanea; Charles-Antoine Collins-Fekete; Sam Beddar
Journal:  Nucl Instrum Methods Phys Res A       Date:  2021-12-16       Impact factor: 1.455

3.  Experimental validation of the TOPAS Monte Carlo system for passive scattering proton therapy.

Authors:  M Testa; J Schümann; H-M Lu; J Shin; B Faddegon; J Perl; H Paganetti
Journal:  Med Phys       Date:  2013-12       Impact factor: 4.071

4.  Using CBCT for pretreatment range check in proton therapy: a phantom study for prostate treatment by anterior-posterior beam.

Authors:  El Hassane Bentefour; Stefan Both; Shikui Tang; Hsiao-Ming Lu
Journal:  J Appl Clin Med Phys       Date:  2015-11-08       Impact factor: 2.102

5.  Time-resolved diode dosimetry calibration through Monte Carlo modeling for in vivo passive scattered proton therapy range verification.

Authors:  Allison Toltz; Michaela Hoesl; Jan Schuemann; Jan Seuntjens; Hsiao-Ming Lu; Harald Paganetti
Journal:  J Appl Clin Med Phys       Date:  2017-10-29       Impact factor: 2.102

  5 in total

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