L-J Ban1, W-Z Lei, Y Liu, Y-P Gong, Y Zeng, L Yang, W Zhang. 1. Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang St, 610041 Chengdu, Sichuan, People's Republic of China.
Abstract
PURPOSE: The aim of the present randomized clinical study was to assess the efficacy of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs, compare analgesia of three different concentrations of lidocaine, and explore use of lower concentrations of lidocaine in local anesthesia for inguinal hernia mesh-repairs. METHODS: A total of 102 consecutive patients undergoing inguinal hernia repairs were randomized to three groups: group A (n = 34) received solution with a lidocaine concentration of 8 mg/mL, group B (n = 34) received a lidocaine concentration of 5 mg/mL, and in group C (n = 34) the lidocaine level was reduced to 3.3 mg/mL. Intraoperative pain and pain at 24 h and 48 h postoperatively were assessed by means of a visual analogue scale. Volume and doses of lidocaine used in local anesthesia were strictly recorded. RESULTS: The efficacy of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs was excellent, no patient required conversion to general anesthesia. The mean pain scores were not significantly different among the three groups. CONCLUSIONS: The local anesthesia technique was good with lidocaine alone in local anesthesia for inguinal hernia mesh-repairs. A concentration of 3.3 mg/mL lidocaine provided similar analgesia as 5 or 8 mg/mL lidocaine.
RCT Entities:
PURPOSE: The aim of the present randomized clinical study was to assess the efficacy of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs, compare analgesia of three different concentrations of lidocaine, and explore use of lower concentrations of lidocaine in local anesthesia for inguinal hernia mesh-repairs. METHODS: A total of 102 consecutive patients undergoing inguinal hernia repairs were randomized to three groups: group A (n = 34) received solution with a lidocaine concentration of 8 mg/mL, group B (n = 34) received a lidocaine concentration of 5 mg/mL, and in group C (n = 34) the lidocaine level was reduced to 3.3 mg/mL. Intraoperative pain and pain at 24 h and 48 h postoperatively were assessed by means of a visual analogue scale. Volume and doses of lidocaine used in local anesthesia were strictly recorded. RESULTS: The efficacy of simplex lidocaine in local anesthesia for inguinal hernia mesh-repairs was excellent, no patient required conversion to general anesthesia. The mean pain scores were not significantly different among the three groups. CONCLUSIONS: The local anesthesia technique was good with lidocaine alone in local anesthesia for inguinal hernia mesh-repairs. A concentration of 3.3 mg/mL lidocaine provided similar analgesia as 5 or 8 mg/mL lidocaine.
Authors: M Bay-Nielsen; H Kehlet; L Strand; J Malmstrøm; F H Andersen; P Wara; P Juul; T Callesen Journal: Lancet Date: 2001-10-06 Impact factor: 79.321
Authors: Sergio Alfieri; Fabio Rotondi; Andrea Di Giorgio; Uberto Fumagalli; Antonio Salzano; Dario Di Miceli; Marco Pericoli Ridolfini; Antonio Sgagari; Giovannibattista Doglietto Journal: Ann Surg Date: 2006-04 Impact factor: 12.969