| Literature DB >> 21622068 |
Suzette M Aguilar1, Jacob D Shea, Mudar A Al-Joumayly, Barry D Van Veen, Nader Behdad, Susan C Hagness.
Abstract
We propose the use of a polycaprolactone (PCL)-based thermoplastic mesh as a tissue-immobilization interface for microwave imaging and microwave hyperthermia treatment. An investigation of the dielectric properties of two PCL-based thermoplastic materials in the frequency range of 0.5-3.5 GHz is presented. The frequency-dependent dielectric constant and effective conductivity of the PCL-based thermoplastics are characterized using measurements of microstrip transmission lines fabricated on substrates comprised of the thermoplastic meshes. We also examine the impact of the presence of a PCL-based thermoplastic mesh on microwave breast imaging. We use a numerical test bed comprised of a previously reported 3-D anatomically realistic breast phantom and a multi-frequency microwave inverse scattering algorithm. We demonstrate that the PCL-based thermoplastic material and the assumed biocompatible medium of vegetable oil are sufficiently well matched such that the PCL layer may be neglected by the imaging solution without sacrificing imaging quality. Our results suggest that PCL-based thermoplastics are promising materials as tissue immobilization structures for microwave diagnostic and therapeutic applications.Entities:
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Year: 2011 PMID: 21622068 PMCID: PMC3222748 DOI: 10.1109/TBME.2011.2157918
Source DB: PubMed Journal: IEEE Trans Biomed Eng ISSN: 0018-9294 Impact factor: 4.538