| Literature DB >> 2162113 |
B Rombaut1, R Vrijsen, A Boeyé.
Abstract
In poliovirus-infected HeLa cells incubated as 30 degrees, 14 S subunits are selectively labeled and no virions are assembled. When the temperature is subsequently shifted to 37 degrees, the radioactivity of the 14 S material is transferred mainly to virions, showing that 14 S subunits are virion precursors. When 14 S subunits synthesized at 30 degrees are incubated in vitro at 37 degrees, they assemble to empty capsids.Entities:
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Year: 1990 PMID: 2162113 DOI: 10.1016/0042-6822(90)90502-i
Source DB: PubMed Journal: Virology ISSN: 0042-6822 Impact factor: 3.616