OBJECTIVE: to examine the relationship between combined lifestyle behaviours and quality-adjusted life years (QALYs) in a general population. METHODS: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level ≥50 µmol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007). RESULTS: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs. CONCLUSION: our findings support the view that modifiable lifestyle factors are an important component in health improvement.
OBJECTIVE: to examine the relationship between combined lifestyle behaviours and quality-adjusted life years (QALYs) in a general population. METHODS: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level ≥50 µmol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007). RESULTS: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs. CONCLUSION: our findings support the view that modifiable lifestyle factors are an important component in health improvement.
Authors: David G Menter; Sherri L Patterson; Craig D Logsdon; Scott Kopetz; Anil K Sood; Ernest T Hawk Journal: Cancer Prev Res (Phila) Date: 2014-07-24
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Authors: Heidi P Fransen; Anne M May; Joline W J Beulens; Ellen A Struijk; G Ardine de Wit; Jolanda M A Boer; N Charlotte Onland-Moret; Jeljer Hoekstra; Yvonne T van der Schouw; H Bas Bueno-de-Mesquita; Petra H M Peeters Journal: PLoS One Date: 2014-11-04 Impact factor: 3.240
Authors: W J Pasman; M J van Erk; W A A Klöpping; L Pellis; S Wopereis; S Bijlsma; H F J Hendriks; A F M Kardinaal Journal: Genes Nutr Date: 2013-04-18 Impact factor: 5.523
Authors: Louise Lafortune; Steven Martin; Sarah Kelly; Isla Kuhn; Olivia Remes; Andy Cowan; Carol Brayne Journal: PLoS One Date: 2016-02-04 Impact factor: 3.240