Literature DB >> 21614892

Anti-hyperlipidemic and antioxidant potential of different fractions of Terminalia arjuna Roxb. bark against PX- 407 induced hyperlipidemia.

Saravanan Subramaniam1, Subramaniam Ramachandran, Subasini Uthrapathi, Victor Rajamanickam Gnamanickam, Govinda Prasad Dubey.   

Abstract

The three fractions diethyl ether, ethyl acetate and ethanol. of T. arjuna exerted hypolipidemic and antioxidative effects at two different doses levels of 175 and 350 mg/kg body weight in Poloxamer (PX)-407 induced hyperlipidemic albino Wistar rats. The hypolipidemic and antioxidant effects of T. arjuna fractions were noticed as EtOH > diethyl ether > ethyl acetate. The results suggest that ethanolic fraction of T. arjuna possesses the potent properties of being antioxidant and hypolipidemic than other fractions. In turn, it has therapeutic potential for the prevention of coronary arterial disease.

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Year:  2011        PMID: 21614892

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  9 in total

1.  Short-Term Adjuvant Therapy with Terminalia arjuna Attenuates Ongoing Inflammation and Immune Imbalance in Patients with Stable Coronary Artery Disease: In Vitro and In Vivo Evidence.

Authors:  Divya Kapoor; Dimple Trikha; Rajesh Vijayvergiya; K K Parashar; Deepak Kaul; Veena Dhawan
Journal:  J Cardiovasc Transl Res       Date:  2015-04-01       Impact factor: 4.132

Review 2.  Antioxidant Phytochemicals for the Prevention of Fluoride-Induced Oxidative Stress and Apoptosis: a Review.

Authors:  Linet M Angwa; Yuting Jiang; Junrui Pei; Dianjun Sun
Journal:  Biol Trace Elem Res       Date:  2021-05-18       Impact factor: 3.738

3.  Protective effect of Terminalia arjuna against alcohol induced oxidative damage of rat erythrocyte membranes.

Authors:  Ananda Vardhan Hebbani; Damodara Reddy Vaddi; Padma Priya Dd; Varadacharyulu NCh
Journal:  J Ayurveda Integr Med       Date:  2021-03-14

Review 4.  Revisiting Terminalia arjuna - An Ancient Cardiovascular Drug.

Authors:  Shridhar Dwivedi; Deepti Chopra
Journal:  J Tradit Complement Med       Date:  2014-10

5.  A comparative clinical study of Asanadi Ghanavati and Gomutra Haritaki in Kapha Medo Margavarana (dyslipidemia).

Authors:  Shivam G Joshi; Hari Mohan Chandola; Alankruta R Dave
Journal:  Ayu       Date:  2014-04

6.  In vitro and in vivo Evaluation of CYP1A Interaction Potential of Terminalia Arjuna Bark.

Authors:  Alice Varghese; Nancy Pandita; R S Gaud
Journal:  Indian J Pharm Sci       Date:  2014-03       Impact factor: 0.975

Review 7.  Medicinal properties of Terminalia arjuna (Roxb.) Wight & Arn.: A review.

Authors:  Augustine Amalraj; Sreeraj Gopi
Journal:  J Tradit Complement Med       Date:  2016-03-20

8.  Safety and efficacy evaluation of Ayurvedic treatment (Arjuna powder and Arogyavardhini Vati) in dyslipidemia patients: A pilot prospective cohort clinical study.

Authors:  Gajendra Kumar; Amita Srivastava; Surinder Kumar Sharma; Yogendra Kumar Gupta
Journal:  Ayu       Date:  2012-04

9.  In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin and arjungenin on CYP3A4, CYP2D6 and CYP2C9 enzyme activity in human liver microsomes.

Authors:  Alice Varghese; Jay Savai; Nancy Pandita; Ram Gaud
Journal:  Toxicol Rep       Date:  2015-02-17
  9 in total

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