Literature DB >> 2161401

Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13.

H M Barker1, T A Jones, E F da Cruz e Silva, N K Spurr, D Sheer, P T Cohen.   

Abstract

A cDNA encoding one isoform (PP1 alpha) of the catalytic subunit of human protein phosphatase 1 has been isolated and used to map the human PP1 alpha gene (PPP1A) to chromosome band 11q13 by analysis of somatic cell hybrids and in situ hybridization. Neoplasms that map to 11q13 are discussed in the light of the recent findings that PP1 alpha is a putative tumor suppressor and that it plays a key role in the control of mitosis.

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Year:  1990        PMID： 2161401     DOI： 10.1016/0888-7543(90)90536-4

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  11 in total

1.  Signal transduction pathways in response to protein misfolding in the extracytoplasmic compartments of E. coli: role of two new phosphoprotein phosphatases PrpA and PrpB.

Authors:  D Missiakas; S Raina
Journal:  EMBO J       Date:  1997-04-01       Impact factor: 11.598

2.  Detailed physical map of human chromosomal region 11q12-13 shows high meiotic recombination rate around the MEN1 locus.

Authors:  M Janson; C Larsson; B Werelius; C Jones; T Glaser; Y Nakamura; C P Jones; M Nordenskjöld
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

3.  A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease loci.

Authors:  C W Richard; D A Withers; T C Meeker; S Maurer; G A Evans; R M Myers; D R Cox
Journal:  Am J Hum Genet       Date:  1991-12       Impact factor: 11.025

4.  Molecular cloning and chromosomal localization of a human skeletal muscle PP-1 gamma 1 cDNA.

Authors:  S A Norman; D M Mott
Journal:  Mamm Genome       Date:  1994-01       Impact factor: 2.957

5.  Targeting of a distinctive protein-serine phosphatase to the protein kinase-like domain of the atrial natriuretic peptide receptor.

Authors:  M Chinkers
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-08       Impact factor: 11.205

6.  Catalytically inactive protein phosphatase 2A can bind to polyomavirus middle tumor antigen and support complex formation with pp60(c-src).

Authors:  E Ogris; I Mudrak; E Mak; D Gibson; D C Pallas
Journal:  J Virol       Date:  1999-09       Impact factor: 5.103

7.  A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene.

Authors:  H B Lieberman; K M Hopkins; M Nass; D Demetrick; S Davey
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-26       Impact factor: 11.205

8.  Isolation and mapping of polymorphic cosmid clones used for sublocalization of the multiple endocrine neoplasia type 1 (MEN1) locus.

Authors:  C Larsson; G Weber; E Kvanta; K Lewis; M Janson; C Jones; T Glaser; G Evans; M Nordenskjöld
Journal:  Hum Genet       Date:  1992-05       Impact factor: 4.132

9.  Deficiency in phosphorylase phosphatase activity despite elevated protein phosphatase type-1 catalytic subunit in skeletal muscle from insulin-resistant subjects.

Authors:  B L Nyomba; D L Brautigan; K K Schlender; W Wang; C Bogardus; D M Mott
Journal:  J Clin Invest       Date:  1991-11       Impact factor: 14.808

10.  Molecular and linkage analysis of type-1 protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians.

Authors:  M Prochazka; H Mochizuki; L J Baier; P T Cohen; C Bogardus
Journal:  Diabetologia       Date:  1995-04       Impact factor: 10.122
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