Literature DB >> 2160891

Characterization by T1-oligonucleotide fingerprinting of three strains of human hepatitis A virus isolated in Italy.

L Fiore1, E De Paolis, F Novello, M Divizia, A Panà.   

Abstract

Three human hepatitis A virus strains, all of them isolated in Italy but one acquired abroad, were analyzed by T1-RNAase oligonucleotide mapping and by monoclonal antibody neutralization. The variation among their genomes according to T1-maps was calculated to be about 9%, thus confirming the poor genomic variation assessed by nucleotide sequencing (1-10%). However T1-maps of these Italian isolates were different from those reported in the literature (Weitz and Siegl, 1985). Neutralization by monoclonal antibody caused a reduction in titres of 2-25 log10. This genomic stability, if confirmed, is important with a view to a valuable vaccine.

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Year:  1990        PMID： 2160891     DOI： 10.1007/BF00155545

Source DB:  PubMed          Journal:  Eur J Epidemiol        ISSN： 0393-2990            Impact factor:   8.082


  15 in total

1.  Analysis of the genome of an endogenous, ecotropic retrovirus of the AKR strain of mice: micromethod for detailed characterization of high-molecular-weight RNA.

Authors:  F S Pedersen; W A Haseltine
Journal:  J Virol       Date:  1980-01       Impact factor: 5.103

2.  Antigenic and biochemical characterization of poliovirus type 2 isolated from two cases of paralytic disease.

Authors:  L Fiore; A Pierangeli; F Lombardi; R Santoro; R Crainic; A Venuti; R Perez-Bercoff
Journal:  Intervirology       Date:  1987       Impact factor: 1.763

3.  Preparative two-dimensional polyacrylamide gel electrophoresis of 32 P-labeled RNA.

Authors:  R de Wachter; W Fiers
Journal:  Anal Biochem       Date:  1972-09       Impact factor: 3.365

4.  Antigenic relatedness of two strains of hepatitis A virus determined by cross-neutralization.

Authors:  S M Lemon; L N Binn
Journal:  Infect Immun       Date:  1983-10       Impact factor: 3.441

Review 5.  Rapid evolution of RNA genomes.

Authors:  J Holland; K Spindler; F Horodyski; E Grabau; S Nichol; S VandePol
Journal:  Science       Date:  1982-03-26       Impact factor: 47.728

6.  Nucleotide sequence heterogeneity of an RNA phage population.

Authors:  E Domingo; D Sabo; T Taniguchi; C Weissmann
Journal:  Cell       Date:  1978-04       Impact factor: 41.582

7.  Detection of hepatitis A virus in the stools of healthy people from endemic areas.

Authors:  P De Filippis; M Divizia; A Mele; B Adamo; A Panà
Journal:  Eur J Epidemiol       Date:  1987-06       Impact factor: 8.082

8.  Molecular cloning and partial sequencing of hepatitis A viral cDNA.

Authors:  D L Linemeyer; J G Menke; A Martin-Gallardo; J V Hughes; A Young; S W Mitra
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

9.  Sequence analysis of hepatitis A virus cDNA coding for capsid proteins and RNA polymerase.

Authors:  B M Baroudy; J R Ticehurst; T A Miele; J V Maizel; R H Purcell; S M Feinstone
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

10.  Variation among hepatitis A virus strains. I. Genomic variation detected by T1 oligonucleotide mapping.

Authors:  M Weitz; G Siegl
Journal:  Virus Res       Date:  1985-12       Impact factor: 3.303
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