Literature DB >> 2160794

Treatment of murine coccidioidal meningitis with SCH39304.

J Defaveri1, S H Sun, J R Graybill.   

Abstract

The triazole SCH39304 was compared with itraconazole and fluconazole for treatment of murine coccidioidal meningitis. Mice were treated for 30 days with 1, 5, 10, or 30 mg of each drug per kg of body weight. Survival and brain tissue counts were measured. At equivalent doses, SCH39304 was more effective than the other triazoles.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2160794      PMCID： PMC171663          DOI： 10.1128/AAC.34.4.663

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Efficacy of SCH39304 in murine cryptococcosis.

Authors:  B I Restrepo; J Ahrens; J R Graybill
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191

2.  Pharmacokinetics and tissue penetration of Sch 39304 in granulocytopenic and nongranulocytopenic rabbits.

Authors:  J W Lee; C Lin; D Loebenberg; M Rubin; P A Pizzo; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1989-11       Impact factor: 5.191

3.  Treatment of experimental cryptococcal meningitis and disseminated candidiasis with SCH39304.

Authors:  J R Perfect; K A Wright; M M Hobbs; D T Durack
Journal:  Antimicrob Agents Chemother       Date:  1989-10       Impact factor: 5.191

4.  Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits.

Authors:  J R Perfect; D V Savani; D T Durack
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191

5.  Treatment of murine coccidioidal meningitis with fluconazole (UK 49,858).

Authors:  J R Graybill; S H Sun; J Ahrens
Journal:  J Med Vet Mycol       Date:  1986-04

Review 6.  New antifungal agents.

Authors:  J R Graybill
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-05       Impact factor: 3.267

7.  High-dose ketoconazole for treatment of fungal infections of the central nervous system.

Authors:  P C Craven; J R Graybill; J H Jorgensen; W E Dismukes; B E Levine
Journal:  Ann Intern Med       Date:  1983-02       Impact factor: 25.391

8.  High-dose ketoconazole therapy and adrenal and testicular function in humans.

Authors:  A Pont; J R Graybill; P C Craven; J N Galgiani; W E Dismukes; R E Reitz; D A Stevens
Journal:  Arch Intern Med       Date:  1984-11

9.  Treatment of mycoses with itraconazole.

Authors:  R M Tucker; P L Williams; E G Arathoon; D A Stevens
Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691

10.  Pharmacokinetics of fluconazole in cerebrospinal fluid and serum in human coccidioidal meningitis.

Authors:  R M Tucker; P L Williams; E G Arathoon; B E Levine; A I Hartstein; L H Hanson; D A Stevens
Journal:  Antimicrob Agents Chemother       Date:  1988-03       Impact factor: 5.191
View more
  5 in total

1.  Comparison of SCH 39304 and its isomers, RR 42427 and SS 42426, for treatment of murine cryptococcal and coccidioidal meningitis.

Authors:  R Allendoerfer; R R Yates; A J Marquis; D Loebenberg; M G Rinaldi; J R Graybill
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

2.  Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice.

Authors:  A Cacciapuoti; D Loebenberg; R Parmegiani; B Antonacci; C Norris; E L Moss; F Menzel; T Yarosh-Tomaine; R S Hare; G H Miller
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

3.  Pharmacokinetics of the triazole antifungal agent genaconazole in healthy men after oral and intravenous administration.

Authors:  P Mojaverian; E Radwanski; M B Affrime; M N Cayen; C C Lin
Journal:  Antimicrob Agents Chemother       Date:  1994-12       Impact factor: 5.191

4.  Comparison of itraconazole and fluconazole treatments in a murine model of coccidioidal meningitis.

Authors:  Perparim Kamberi; Raymond A Sobel; Karl V Clemons; Andreas Waldvogel; Joan M Striebel; Paul L Williams; David A Stevens
Journal:  Antimicrob Agents Chemother       Date:  2006-12-18       Impact factor: 5.191

5.  In vitro and in vivo activities of SCH 42427, the active enantiomer of the antifungal agent SCH 39304.

Authors:  D Loebenberg; A Cacciapuoti; R Parmegiani; E L Moss; F Menzel; B Antonacci; C Norris; T Yarosh-Tomaine; R S Hare; G H Miller
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.