Literature DB >> 21607903

Current concepts in fluid resuscitation for prehospital care of combat casualties.

Michael A Dubick1.   

Abstract

Historically, hemorrhage accounts for the primary cause of death on the battlefield in conventional warfare. In addition, hemorrhage was associated with 85% of potentially survivable deaths in the current conflicts, approximately two-thirds of which were from noncompressible injuries. Future combat casualty care strategies suggest the likelihood of long transport times or significant time delays in evacuation of casualties. In addition, there are logistical limitations to providing large volumes of resuscitation fluid far-forward, and current guidelines do not recommend infusing large volumes of fluid until bleeding is controlled. Since the medic has few options for treating noncompressible injuries short of infusing fluid to maintain a blood pressure, the concept of damage control resuscitation was developed to promote hemostatic resuscitation. Damage control resuscitation recommends limiting the amount of crystalloids or colloids infused and using plasma and other blood products in more optimal ratios for the treatment of severe hemorrhage to improve battlefield survival and to reduce or prevent early and late deleterious sequelae. Taken together, these efforts have important implications towards the development of optimal fluid resuscitation strategies for stabilization of the combat casualty.

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Year:  2011        PMID: 21607903

Source DB:  PubMed          Journal:  US Army Med Dep J        ISSN: 1524-0436


  8 in total

1.  Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre-feed.

Authors:  Elizabeth R Lusczek; Tyrone Vincent; Daniel Lexcen; Vishwesh Kulkarni; Kristine Mulier; Greg Beilman
Journal:  BMC Emerg Med       Date:  2015-07-01

2.  Multicenter observational prehospital resuscitation on helicopter study.

Authors:  John B Holcomb; Michael D Swartz; Stacia M DeSantis; Thomas J Greene; Erin E Fox; Deborah M Stein; Eileen M Bulger; Jeffrey D Kerby; Michael Goodman; Martin A Schreiber; Martin D Zielinski; Terence O'Keeffe; Kenji Inaba; Jeffrey S Tomasek; Jeanette M Podbielski; Savitri N Appana; Misung Yi; Charles E Wade
Journal:  J Trauma Acute Care Surg       Date:  2017-07       Impact factor: 3.313

3.  Oral rehydration solutions for burn management in the field and underdeveloped regions: a review.

Authors:  Krishna S Vyas; Lesley K Wong
Journal:  Int J Burns Trauma       Date:  2013-07-08

Review 4.  Wilderness medicine.

Authors:  Douglas G Sward; Brad L Bennett
Journal:  World J Emerg Med       Date:  2014

5.  Microparticles from aged packed red blood cell units stimulate pulmonary microthrombus formation via P-selectin.

Authors:  Young Kim; Michael D Goodman; Andrew D Jung; William A Abplanalp; Rebecca M Schuster; Charles C Caldwell; Alex B Lentsch; Timothy A Pritts
Journal:  Thromb Res       Date:  2019-11-26       Impact factor: 3.944

6.  Vasopressin Infusion with Small-Volume Fluid Resuscitation during Hemorrhagic Shock Promotes Hemodynamic Stability and Survival in Swine.

Authors:  Raúl J Gazmuri; Kasen Whitehouse; Karla Whittinghill; Alvin Baetiong; Jeejabai Radhakrishnan
Journal:  PLoS One       Date:  2015-06-24       Impact factor: 3.240

7.  Fed state prior to hemorrhagic shock and polytrauma in a porcine model results in altered liver transcriptomic response.

Authors:  Charles Determan; Rebecca Anderson; Aaron Becker; Nancy Witowski; Elizabeth Lusczek; Kristine Mulier; Greg J Beilman
Journal:  PLoS One       Date:  2014-06-17       Impact factor: 3.240

8.  Host responses to concurrent combined injuries in non-human primates.

Authors:  Matthew J Bradley; Diego A Vicente; Benjamin A Bograd; Erin M Sanders; Crystal L Leonhardt; Eric A Elster; Thomas A Davis
Journal:  J Inflamm (Lond)       Date:  2017-11-02       Impact factor: 4.981

  8 in total

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