PURPOSE: The purpose of this study was to evaluate in vivo the influence of inversion pulse slice selectivity on oxygen-enhanced magnetic resonance imaging (MRI). MATERIALS AND METHODS: Thirteen healthy volunteers were studied with a two-dimensional cardiac- and respiratory-gated adiabatic inversion-recovery half-Fourier single-shot turbo spin-echo (HASTE) sequence with either slice-selective or non-slice-selective inversion recovery (IR) pulse at inversion times increasing from 300 to 1400 ms. The signal-to-noise ratio (SNR) at every inversion time (TI), real signal difference (ΔSI), and relative enhancement ratio of lung parenchyma at TI ≥ 800 ms were statistically compared for oxygen-enhanced and non-oxygen-enhanced MR images with slice-selective or non-slice-selective IR pulses. RESULTS: The SNRs of acquisitions with slice-selective IR pulses were significantly higher than those of non-slice-selective IR pulses (P < 0.05). At TI 800 ms, the ΔSI of lung parenchyma on IR-HASTE images with slice-selective inversion pulse type was significantly higher than on that with the non-slice-selective type (P < 0.05). Relative enhancement ratios of the slice-selective IR pulses were significantly lower than those of non-slice-selective IR pulses at TIs between 800 and 1400 ms (P < 0.05). CONCLUSION: Slice selectivity of inversion pulse type affects oxygen-enhanced MRI in vivo.
PURPOSE: The purpose of this study was to evaluate in vivo the influence of inversion pulse slice selectivity on oxygen-enhanced magnetic resonance imaging (MRI). MATERIALS AND METHODS: Thirteen healthy volunteers were studied with a two-dimensional cardiac- and respiratory-gated adiabatic inversion-recovery half-Fourier single-shot turbo spin-echo (HASTE) sequence with either slice-selective or non-slice-selective inversion recovery (IR) pulse at inversion times increasing from 300 to 1400 ms. The signal-to-noise ratio (SNR) at every inversion time (TI), real signal difference (ΔSI), and relative enhancement ratio of lung parenchyma at TI ≥ 800 ms were statistically compared for oxygen-enhanced and non-oxygen-enhanced MR images with slice-selective or non-slice-selective IR pulses. RESULTS: The SNRs of acquisitions with slice-selective IR pulses were significantly higher than those of non-slice-selective IR pulses (P < 0.05). At TI 800 ms, the ΔSI of lung parenchyma on IR-HASTE images with slice-selective inversion pulse type was significantly higher than on that with the non-slice-selective type (P < 0.05). Relative enhancement ratios of the slice-selective IR pulses were significantly lower than those of non-slice-selective IR pulses at TIs between 800 and 1400 ms (P < 0.05). CONCLUSION: Slice selectivity of inversion pulse type affects oxygen-enhanced MRI in vivo.
Authors: Vu M Mai; Sean Tutton; Pottumarthi V Prasad; Qun Chen; Wei Li; Chi Chen; Benjamin Liu; Jason Polzin; Saban Kurucay; Robert R Edelman Journal: Magn Reson Med Date: 2003-03 Impact factor: 4.668
Authors: Vasiliki Demas; Dimitris Sakellariou; Carlos A Meriles; Songi Han; Jeffrey Reimer; Alexander Pines Journal: Proc Natl Acad Sci U S A Date: 2004-06-07 Impact factor: 11.205
Authors: Q Chen; D L Levin; D Kim; V David; M McNicholas; V Chen; P M Jakob; M A Griswold; J W Goldfarb; H Hatabu; R R Edelman Journal: Radiology Date: 1999-12 Impact factor: 11.105