Literature DB >> 21604917

The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for hepatic steatosis.

José A M Carvalho1, Noël C Barengo, Jaakko Tuomilehto, Raquel D Conceição, Raul D Santos.   

Abstract

INTRODUCTION. Hepatic steatosis due to non-alcoholic fatty liver disease is associated with obesity, dyslipidemia, insulin resistance, and type 2 diabetes. The Finnish Diabetes Risk Score (FINDRISC) is a prognostic screening tool to detect people at risk for type 2 diabetes without the use of any blood test. The objective of this study was to evaluate whether FINDRISC can also be used to screen for the presence of hepatic steatosis. PATIENTS AND METHODS. Steatosis was determined by ultrasound. The study sample consisted of 821 non-diabetic subjects without previous hepatic disease; 81% were men (mean age 45 ± 9 years) and 19% women (mean age 41 ± 10 years). RESULTS. Steatosis was present in 44% of men and 10% of women. The odds ratio for one unit increase in the FINDRISC associated with the risk of steatosis was 1.30 (95% CI 1.25-1.35), similar for men and women. The area under the receiver operating characteristics curve for steatosis was 0.80 (95% CI 0.77-0.83); 0.80 in men (95% CI 0.77-0.83) and 0.83 (95% CI 0.73-0.93) in women. CONCLUSIONS. Our data suggest that the FINDRISC could be a useful primary screening tool for the presence of steatosis.

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Year:  2011        PMID: 21604917     DOI: 10.3109/07853890.2011.554428

Source DB:  PubMed          Journal:  Ann Med        ISSN: 0785-3890            Impact factor:   4.709


  6 in total

1.  A simple Indian diabetes risk score could help identify nondiabetic individuals at high risk of non-alcoholic fatty liver disease (CURES-117).

Authors:  Viknesh Prabu Anbalagan; Vijayachandrika Venkataraman; Mamilla Vamsi; Mohan Deepa; Viswanathan Mohan
Journal:  J Diabetes Sci Technol       Date:  2012-11-01

Review 2.  Gaps in Guidelines for the Management of Diabetes in Low- and Middle-Income Versus High-Income Countries-A Systematic Review.

Authors:  Mayowa O Owolabi; Joseph O Yaria; Meena Daivadanam; Akintomiwa I Makanjuola; Gary Parker; Brian Oldenburg; Rajesh Vedanthan; Shane Norris; Ayodele R Oguntoye; Morenike A Osundina; Omarys Herasme; Sulaiman Lakoh; Luqman O Ogunjimi; Sarah E Abraham; Paul Olowoyo; Carolyn Jenkins; Wuwei Feng; Hernán Bayona; Sailesh Mohan; Rohina Joshi; Ruth Webster; Andre P Kengne; Antigona Trofor; Lucia Maria Lotrean; Devarsetty Praveen; Jessica H Zafra-Tanaka; Maria Lazo-Porras; Kirsten Bobrow; Michaela A Riddell; Konstantinos Makrilakis; Yannis Manios; Bruce Ovbiagele
Journal:  Diabetes Care       Date:  2018-05       Impact factor: 19.112

3.  Association between non-alcoholic hepatic steatosis and hyper reactive blood pressure response on the exercise treadmill test.

Authors:  A G Laurinavicius; M S Bittencourt; M J Blaha; F C Nary; N M Kashiwagi; R D Conceiçao; R S Meneghelo; R R Prado; J A M Carvalho; K Nasir; R S Blumenthal; R D Santos
Journal:  QJM       Date:  2016-01-19

4.  Associations of Erythrocyte Fatty Acids in the De Novo Lipogenesis Pathway with Proxies of Liver Fat Accumulation in the EPIC-Potsdam Study.

Authors:  Simone Jacobs; Susanne Jäger; Eugene Jansen; Andreas Peter; Norbert Stefan; Heiner Boeing; Matthias B Schulze; Janine Kröger
Journal:  PLoS One       Date:  2015-05-18       Impact factor: 3.240

5.  Physical activity as a protective factor for development of non-alcoholic fatty liver in men.

Authors:  Carla Giuliano de Sá Pinto; Marcio Marega; José Antonio Maluf de Carvalho; Felipe Gambetta Carmona; Carlos Eduardo Felix Lopes; Fabio Luis Ceschini; Danilo Sales Bocalini; Aylton José Figueira Junior
Journal:  Einstein (Sao Paulo)       Date:  2015 Jan-Mar

6.  Combination of diabetes risk factors and hepatic steatosis in Chinese: the Cardiometabolic Risk in Chinese (CRC) Study.

Authors:  Jun Liang; Yu Wang; Hongyan Li; Xuekui Liu; Qinqin Qiu; Lu Qi
Journal:  PLoS One       Date:  2014-03-03       Impact factor: 3.240

  6 in total

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