Literature DB >> 21604076

Age and receipt of guideline-recommended medications for heart failure: a nationwide study of veterans.

Michael A Steinman1, John B Harlow, Barry M Massie, Peter J Kaboli, Kathy Z Fung, Paul A Heidenreich.   

Abstract

BACKGROUND: Older patients often receive less guideline-concordant care for heart failure than younger patients.
OBJECTIVE: To determine whether age differences in heart failure care are explained by patient, provider, and health system characteristics and/or by chart-documented reasons for non-adherence to guidelines. DESIGN AND PATIENTS: Retrospective cohort study of 2,772 ambulatory veterans with heart failure and left ventricular ejection fraction <40% from a 2004 nationwide medical record review program (the VA External Peer Review Program). MAIN MEASURES: Ambulatory use of ACE inhibitors, angiotensin receptor blockers (ARBs), and beta blockers.
RESULTS: Among 2,772 patients, mean age was 73 +/- 10 years, 87% received an ACE inhibitor or ARB, and 82% received a beta blocker. When patients with explicit chart-documented reasons for not receiving these drugs were excluded, 95% received an ACE inhibitor or ARB and 89% received a beta blocker. In multivariable analyses controlling for a variety of patient and health system characteristics, the adjusted odds ratio for ACE-inhibitor and ARB use was 0.43 (95% CI 0.24-0.78) for patients age 80 and over vs. those age 50-64 years, and the adjusted odds ratio for beta blocker use was 0.66 (95% CI 0.48-0.93) between the two age groups. The magnitude of these associations was similar but not statistically significant after excluding patients with chart-documented reasons for not prescribing ACE inhibitors or ARBs and beta blockers.
CONCLUSIONS: A high proportion of veterans receive guideline-recommended medications for heart failure. Older veterans are consistently less likely to receive these drugs, although these differences were no longer significant when accounting for patients with chart-documented reasons for not prescribing these drugs. Closely evaluating reasons for non-prescribing in older adults is essential to assessing whether non-treatment represents good clinical judgment or missed opportunities to improve care.

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Year:  2011        PMID: 21604076      PMCID: PMC3181303          DOI: 10.1007/s11606-011-1745-2

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  44 in total

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2.  Barriers to diagnosing and managing heart failure in primary care.

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4.  Gender, age, and heart failure with preserved left ventricular systolic function.

Authors:  Frederick A Masoudi; Edward P Havranek; Grace Smith; Ronald H Fish; John F Steiner; Diana L Ordin; Harlan M Krumholz
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5.  Time trends in the use of beta-blockers and other pharmacotherapies in older adults with congestive heart failure.

Authors:  Nicholas L Smith; Jeannie D Chan; Thomas D Rea; Kerri L Wiggins; John S Gottdiener; Thomas Lumley; Bruce M Psaty
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6.  National patterns of use and effectiveness of angiotensin-converting enzyme inhibitors in older patients with heart failure and left ventricular systolic dysfunction.

Authors:  Frederick A Masoudi; Saif S Rathore; Yongfei Wang; Edward P Havranek; Jeptha P Curtis; JoAnne Micale Foody; Harlan M Krumholz
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8.  Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina.

Authors:  Alain G Bertoni; Vanessa Duren-Winfield; Walter T Ambrosius; Jill McArdle; Carla A Sueta; Mark W Massing; Sharon Peacock; Jennifer Davis; Janet B Croft; David C Goff
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9.  Relation of sex, age and concomitant diseases to drug prescription for heart failure in primary care in Europe.

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10.  Age is not a significant risk factor for failed trial of beta-blocker therapy in older patients with chronic heart failure.

Authors:  Miles D Witham; Neil D Gillespie; Allan D Struthers
Journal:  Age Ageing       Date:  2004-06-24       Impact factor: 10.668

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2.  Reasons for not prescribing guideline-recommended medications to adults with heart failure.

Authors:  Michael A Steinman; Liezel Dimaano; Carolyn A Peterson; Paul A Heidenreich; Sara J Knight; Kathy Z Fung; Peter J Kaboli
Journal:  Med Care       Date:  2013-10       Impact factor: 2.983

3.  Unlocking echocardiogram measurements for heart disease research through natural language processing.

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4.  Engaging Cardiology Providers in Quality Measurement.

Authors:  Paul Heidenreich; Alex Sandhu; Richard Schofield
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