Literature DB >> 21603084

SOLVING PDES IN COMPLEX GEOMETRIES: A DIFFUSE DOMAIN APPROACH.

X Li1, J Lowengrub, A Rätz, A Voigt.   

Abstract

We extend previous work and present a general approach for solving partial differential equations in complex, stationary, or moving geometries with Dirichlet, Neumann, and Robin boundary conditions. Using an implicit representation of the geometry through an auxilliary phase field function, which replaces the sharp boundary of the domain with a diffuse layer (e.g. diffuse domain), the equation is reformulated on a larger regular domain. The resulting partial differential equation is of the same order as the original equation, with additional lower order terms to approximate the boundary conditions. The reformulated equation can be solved by standard numerical techniques. We use the method of matched asymptotic expansions to show that solutions of the re-formulated equations converge to those of the original equations. We provide numerical simulations which confirm this analysis. We also present applications of the method to growing domains and complex three-dimensional structures and we discuss applications to cell biology and heteroepitaxy.

Entities:  

Year:  2009        PMID: 21603084      PMCID: PMC3097555          DOI: 10.4310/cms.2009.v7.n1.a4

Source DB:  PubMed          Journal:  Commun Math Sci        ISSN: 1539-6746            Impact factor:   1.120


  6 in total

1.  Computational approach for modeling intra- and extracellular dynamics.

Authors:  Julien Kockelkoren; Herbert Levine; Wouter-Jan Rappel
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2003-09-26

2.  Modeling wave propagation in realistic heart geometries using the phase-field method.

Authors:  Flavio H Fenton; Elizabeth M Cherry; Alain Karma; Wouter-Jan Rappel
Journal:  Chaos       Date:  2005-03       Impact factor: 3.642

3.  Membrane-bound Turing patterns.

Authors:  Herbert Levine; Wouter-Jan Rappel
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2005-12-19

4.  Diffusion on a Curved Surface Coupled to Diffusion in the Volume: Application to Cell Biology.

Authors:  Igor L Novak; Fei Gao; Yung-Sze Choi; Diana Resasco; James C Schaff; Boris M Slepchenko
Journal:  J Comput Phys       Date:  2007-10-01       Impact factor: 3.553

5.  A New Ghost Cell/Level Set Method for Moving Boundary Problems: Application to Tumor Growth.

Authors:  Paul Macklin; John S Lowengrub
Journal:  J Sci Comput       Date:  2008-06-01       Impact factor: 2.592

6.  Phase-field modeling of the dynamics of multicomponent vesicles: Spinodal decomposition, coarsening, budding, and fission.

Authors:  John S Lowengrub; Andreas Rätz; Axel Voigt
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2009-03-31
  6 in total
  19 in total

1.  Signaling networks and cell motility: a computational approach using a phase field description.

Authors:  Wieland Marth; Axel Voigt
Journal:  J Math Biol       Date:  2013-07-09       Impact factor: 2.259

2.  A DIFFUSE-INTERFACE APPROACH FOR MODELING TRANSPORT, DIFFUSION AND ADSORPTION/DESORPTION OF MATERIAL QUANTITIES ON A DEFORMABLE INTERFACE.

Authors:  Knut Erik Teigen; Xiangrong Li; John Lowengrub; Fan Wang; Axel Voigt
Journal:  Commun Math Sci       Date:  2009-12       Impact factor: 1.120

3.  Particles at fluid-fluid interfaces: A new Navier-Stokes-Cahn-Hilliard surface- phase-field-crystal model.

Authors:  Sebastian Aland; John Lowengrub; Axel Voigt
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2012-10-25

4.  Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns.

Authors:  Brian A Camley; Yunsong Zhang; Yanxiang Zhao; Bo Li; Eshel Ben-Jacob; Herbert Levine; Wouter-Jan Rappel
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-25       Impact factor: 11.205

5.  A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane.

Authors:  Ying Chen; Steven M Wise; Vivek B Shenoy; John S Lowengrub
Journal:  Int J Numer Method Biomed Eng       Date:  2014-01-17       Impact factor: 2.747

6.  Two-phase flow in complex geometries: A diffuse domain approach.

Authors:  S Aland; J Lowengrub; A Voigt
Journal:  Comput Model Eng Sci       Date:  2010       Impact factor: 1.593

7.  Mechanisms of Cell Polarization.

Authors:  Wouter-Jan Rappel; Leah Edelstein-Keshet
Journal:  Curr Opin Syst Biol       Date:  2017-04-12

8.  Tumor growth and calcification in evolving microenvironmental geometries.

Authors:  Ying Chen; John S Lowengrub
Journal:  J Theor Biol       Date:  2018-12-05       Impact factor: 2.691

9.  A diffuse-interface method for two-phase flows with soluble surfactants.

Authors:  Knut Erik Teigen; Peng Song; John Lowengrub; Axel Voigt
Journal:  J Comput Phys       Date:  2011-01-20       Impact factor: 3.553

10.  Tumor growth in complex, evolving microenvironmental geometries: a diffuse domain approach.

Authors:  Ying Chen; John S Lowengrub
Journal:  J Theor Biol       Date:  2014-07-09       Impact factor: 2.691

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