Literature DB >> 21601846

The impact of the learning curve on adhesion formation in a laparoscopic mouse model.

Roberta Corona1, Jasper Verguts, Maria Mercedes Binda, Carlos Roger Molinas, Ron Schonman, Philippe R Koninckx.   

Abstract

OBJECTIVE: To evaluate the impact of surgeon training on adhesion formation in a laparoscopic mouse model. Laparoscopic surgery and bowel manipulation was demonstrated to enhance postoperative adhesion formation.
DESIGN: Prospective randomized, controlled trial.
SETTING: University laboratory research center. ANIMAL(S): 200 BALB/c and 200 Swiss female mice. INTERVENTION(S): Adhesions were induced by opposing bipolar lesions and 60 minutes of pneumoperitoneum. Each surgeon operated on 80 mice (40 Swiss and 40 BALB/c), the only variable thus being his/her increasing experience. Some surgeons were already experienced gynecologists, others were starting their training. MAIN OUTCOME MEASURE(S): End points were the duration of surgery while performing the lesions. The adhesion formation was scored quantitatively (proportion and total) and qualitatively (extent, type, and tenacity) after 7 days. RESULT(S): With training, duration of surgery and adhesion formation decreased exponentially for all surgeons, whether experienced or not. Experienced surgeons had initially a shorter duration of surgery, less adhesion formation, and less de novo adhesions than inexperienced surgeons. CONCLUSION(S): These data suggest that laparoscopic skills improve with training, leading to a decrease in the duration of surgery and formation of adhesions. Therefore completion of a standardized learning curve should be mandatory when initiating adhesion formation studies both in laboratory or clinical setting.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21601846     DOI: 10.1016/j.fertnstert.2011.04.057

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  6 in total

Review 1.  Peritoneal adhesions after laparoscopic gastrointestinal surgery.

Authors:  Valerio Mais
Journal:  World J Gastroenterol       Date:  2014-05-07       Impact factor: 5.742

2.  Response to comment on "Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation".

Authors:  Ben-Shian Huang; Huann-Cheng Horng; Peng-Hui Wang; Muh-Hwa Yang; Yi-Jen Chen
Journal:  Reprod Biol Endocrinol       Date:  2017-07-20       Impact factor: 5.211

Review 3.  Mouse Anesthesia: The Art and Science.

Authors:  Kaela L Navarro; Monika Huss; Jennifer C Smith; Patrick Sharp; James O Marx; Cholawat Pacharinsak
Journal:  ILAR J       Date:  2021-12-31       Impact factor: 1.521

4.  Peritoneal full-conditioning reduces postoperative adhesions and pain: a randomised controlled trial in deep endometriosis surgery.

Authors:  Philippe R Koninckx; Roberta Corona; Dirk Timmerman; Jasper Verguts; Leila Adamyan
Journal:  J Ovarian Res       Date:  2013-12-11       Impact factor: 4.234

5.  Editorial.

Authors:  S Gordts
Journal:  Facts Views Vis Obgyn       Date:  2015

6.  The Improvement of Laparoscopic Surgical Skills Obtained by Gynecologists after Ten Years of Clinical Training Can Reduce Peritoneal Adhesion Formation during Laparoscopic Myomectomy: A Retrospective Cohort Study.

Authors:  Valerio Mais; Michele Peiretti; Luigi Minerba
Journal:  Biomed Res Int       Date:  2017-12-19       Impact factor: 3.411

  6 in total

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