Literature DB >> 21599030

Synthesis of NanoQ, a copper-based contrast agent for high-resolution magnetic resonance imaging characterization of human thrombus.

Dipanjan Pan1, Shelton D Caruthers, Angana Senpan, Ceren Yalaz, Allen J Stacy, Grace Hu, Jon N Marsh, Patrick J Gaffney, Samuel A Wickline, Gregory M Lanza.   

Abstract

A new site-targeted molecular imaging contrast agent based on a nanocolloidal suspension of lipid-encapsulated, organically soluble divalent copper has been developed. Concentrating a high payload of divalent copper ions per nanoparticle, this agent provides a high per-particle r1 relaxivity, allowing sensitive detection in T1-weighted magnetic resonance imaging when targeted to fibrin clots in vitro. The particle also exhibits a defined clearance and safety profile in vivo.

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Year:  2011        PMID： 21599030      PMCID： PMC3124378          DOI： 10.1021/ja201918u

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  29 in total

Review 1.  Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility.

Authors:  Rachel K O'Reilly; Craig J Hawker; Karen L Wooley
Journal:  Chem Soc Rev       Date:  2006-10-02       Impact factor: 54.564

2.  Development of a T1 contrast agent for magnetic resonance imaging using MnO nanoparticles.

Authors:  Hyon Bin Na; Jung Hee Lee; Kwangjin An; Yong Il Park; Mihyun Park; In Su Lee; Do-Hyun Nam; Sung Tae Kim; Seung-Hoon Kim; Sang-Wook Kim; Keun-Ho Lim; Ki-Soo Kim; Sun-Ok Kim; Taeghwan Hyeon
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

3.  Hollow manganese oxide nanoparticles as multifunctional agents for magnetic resonance imaging and drug delivery.

Authors:  Jongmin Shin; Rahman Md Anisur; Mi Kyeong Ko; Geun Ho Im; Jung Hee Lee; In Su Lee
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

Review 4.  The convergence of synthetic organic and polymer chemistries.

Authors:  Craig J Hawker; Karen L Wooley
Journal:  Science       Date:  2005-08-19       Impact factor: 47.728

5.  Conquering the dark side: colloidal iron oxide nanoparticles.

Authors:  Angana Senpan; Shelton D Caruthers; Ilsu Rhee; Nicholas A Mauro; Dipanjan Pan; Grace Hu; Michael J Scott; Ralph W Fuhrhop; Patrick J Gaffney; Samuel A Wickline; Gregory M Lanza
Journal:  ACS Nano       Date:  2009-12-22       Impact factor: 15.881

6.  Molecular imaging of angiogenesis in early-stage atherosclerosis with alpha(v)beta3-integrin-targeted nanoparticles.

Authors:  Patrick M Winter; Anne M Morawski; Shelton D Caruthers; Ralph W Fuhrhop; Huiying Zhang; Todd A Williams; John S Allen; Elizabeth K Lacy; J David Robertson; Gregory M Lanza; Samuel A Wickline
Journal:  Circulation       Date:  2003-10-13       Impact factor: 29.690

Review 7.  Magnetic resonance imaging of vulnerable atherosclerotic plaques: current imaging strategies and molecular imaging probes.

Authors:  Karen C Briley-Saebo; Willem J M Mulder; Venkatesh Mani; Fabien Hyafil; Vardan Amirbekian; Juan Gilberto S Aguinaldo; Edward A Fisher; Zahi A Fayad
Journal:  J Magn Reson Imaging       Date:  2007-09       Impact factor: 4.813

Review 8.  Biochemical safety profiles of gadolinium-based extracellular contrast agents and nephrogenic systemic fibrosis.

Authors:  Hale Ersoy; Frank J Rybicki
Journal:  J Magn Reson Imaging       Date:  2007-11       Impact factor: 4.813

Review 9.  Coronary thrombosis: pathogenesis and clinical manifestations.

Authors:  E Falk
Journal:  Am J Cardiol       Date:  1991-09-03       Impact factor: 2.778

10.  Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI.

Authors:  Eyk A Schellenberger; Alexei Bogdanov; Dagmar Högemann; Jonathan Tait; Ralph Weissleder; Lee Josephson
Journal:  Mol Imaging       Date:  2002 Apr-Jun       Impact factor: 4.488
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  11 in total

Review 1.  An unmet clinical need: The history of thrombus imaging.

Authors:  Gregory M Lanza; Grace Cui; Anne H Schmieder; Huiying Zhang; John S Allen; Michael J Scott; Todd Williams; Xiaoxia Yang
Journal:  J Nucl Cardiol       Date:  2017-06-12       Impact factor: 5.952

Review 2.  Nanoformulations for molecular MRI.

Authors:  Chuqiao Tu; Angelique Y Louie
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2012-04-06

Review 3.  Molecular imaging of atherosclerosis with nanoparticle-based fluorinated MRI contrast agents.

Authors:  Rohun U Palekar; Andrew P Jallouk; Gregory M Lanza; Hua Pan; Samuel A Wickline
Journal:  Nanomedicine (Lond)       Date:  2015       Impact factor: 5.307

4.  Discrete bimodal probes for thrombus imaging.

Authors:  Ritika Uppal; Kate L Ciesienski; Daniel B Chonde; Galen S Loving; Peter Caravan
Journal:  J Am Chem Soc       Date:  2012-06-20       Impact factor: 15.419

5.  Fibrin-targeted PET probes for the detection of thrombi.

Authors:  Katie L Ciesienski; Yan Yang; Ilknur Ay; Daniel B Chonde; Galen S Loving; Tyson A Rietz; Ciprian Catana; Peter Caravan
Journal:  Mol Pharm       Date:  2013-01-30       Impact factor: 4.939

6.  Molecular imaging of fibrin in a breast cancer xenograft mouse model.

Authors:  Ritika Uppal; Zdravka Medarova; Christian T Farrar; Guangping Dai; Anna Moore; Peter Caravan
Journal:  Invest Radiol       Date:  2012-10       Impact factor: 6.016

Review 7.  Current trends in pyrrole and porphyrin-derived nanoscale materials for biomedical applications.

Authors:  Parinaz Fathi; Dipanjan Pan
Journal:  Nanomedicine (Lond)       Date:  2020-09-25       Impact factor: 5.307

8.  alphaVbeta3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment.

Authors:  Ruiying Zhang; Dipanjan Pan; Xin Cai; Xiaoxia Yang; Angana Senpan; John S Allen; Gregory M Lanza; Lihong V Wang
Journal:  Theranostics       Date:  2015-01-01       Impact factor: 11.556

9.  Enhancing Tumor Accumulation and Cellular Uptake of Layered Double Hydroxide Nanoparticles by Coating/Detaching pH-Triggered Charge-Convertible Polymers.

Authors:  Tiefeng Xu; Jianping Liu; Luyao Sun; Run Zhang; Zhi Ping Xu; Qing Sun
Journal:  ACS Omega       Date:  2021-01-27

10.  Copper-Catalyzed Syntheses of Pyrene-Pyrazole Pharmacophores and Structure Activity Studies for Tubulin Polymerization.

Authors:  Dinabandhu Sar; Indrajit Srivastava; Santosh K Misra; Fatemeh Ostadhossein; Parinaz Fathi; Dipanjan Pan
Journal:  ACS Omega       Date:  2018-06-13
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