| Literature DB >> 21597912 |
Seong Yeon Yoo1, Nam Soo Cho, Myung Jin Park, Ki Min Seong, Jung Ho Hwang, Seok Bean Song, Myun Soo Han, Won Tae Lee, Ki Wha Chung.
Abstract
Genotyping of highly polymorphic short tandem repeat (STR) markers is widely used for the genetic identification of individuals in forensic DNA analyses and in paternity disputes. The National DNA Profile Databank recently established by the DNA Identification Act in Korea contains the computerized STR DNA profiles of individuals convicted of crimes. For the establishment of a large autosomal STR loci population database, 1805 samples were obtained at random from Korean individuals and 15 autosomal STR markers were analyzed using the AmpFlSTR Identifiler PCR Amplification kit. For the 15 autosomal STR markers, no deviations from the Hardy-Weinberg equilibrium were observed. The most informative locus in our data set was the D2S1338 with a discrimination power of 0.9699. The combined matching probability was 1.521 × 10(-17). This large STR profile dataset including atypical alleles will be important for the establishment of the Korean DNA database and for forensic applications.Mesh：
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Year: 2011 PMID： 21597912 PMCID： PMC3887661 DOI： 10.1007/s10059-011-2288-4
Source DB: PubMed Journal: Mol Cells ISSN： 1016-8478 Impact factor: 5.034