Literature DB >> 21596

Estimation of plasma lorazepam by gas-liquid chromatography and a benzene extraction.

P J Howard, J K Lilburn, J W Dundee, W Toner, P D McIlroy.   

Abstract

Plasma lorazepam can be easily and reliably estimated using a simple single stage benzene extraction and gas-lizuid chromatography with flunitrazepam as the internal standard. Reproducible results within the clinical range of plasma levels were obtained. This method permits the extraction and chromatographing of 40 samples in approximately 7 1/2 hours.

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Year:  1977        PMID: 21596     DOI: 10.1111/j.1365-2044.1977.tb10078.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  3 in total

1.  The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam.

Authors:  W A McGowan; J W Dundee
Journal:  Br J Clin Pharmacol       Date:  1982-08       Impact factor: 4.335

2.  A study of conjugation and drug elimination in the human neonate.

Authors:  A J Cummings; A G Whitelaw
Journal:  Br J Clin Pharmacol       Date:  1981-10       Impact factor: 4.335

Review 3.  Clinical pharmacokinetics of oxazepam and lorazepam.

Authors:  D J Greenblatt
Journal:  Clin Pharmacokinet       Date:  1981 Mar-Apr       Impact factor: 6.447

  3 in total

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