Literature DB >> 6125205

The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam.

W A McGowan, J W Dundee.   

Abstract

1 The effect of intravenous cimetidine 200 mg or 400 mg on the absorption of lorazepam 2.5 mg tablet and diazepam 10 mg tablet and capsule was studied. 2 Considerable individual variation in plasma concentrations was found with all preparations. 3 Cimetidine increased the absorption of diazepam and lorazepam. 4 Capsule preparations of diazepam generally produced higher drug plasma concentrations than the tablets.

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Year:  1982        PMID： 6125205      PMCID： PMC1427731          DOI： 10.1111/j.1365-2125.1982.tb01963.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  21 in total

1.  Estimation of plasma diazepam. Critique of a method using gas-liquid chromatography and benzene extraction.

Authors:  J A Gamble; R A Assaf; J S Mackay; M S Kennedy; P J Howard
Journal:  Anaesthesia       Date:  1975-03       Impact factor: 6.955

2.  Proceedings: Problems of ejection from aircraft. Spinal ejection injuries.

Authors:  C R Griffin
Journal:  Proc R Soc Med       Date:  1975-11

Review 3.  Factors affecting gastrointestinal absorption of drugs.

Authors:  R R Levine
Journal:  Am J Dig Dis       Date:  1970-02

Review 4.  Drugs, diseases and altered gastric emptying.

Authors:  W S Nimmo
Journal:  Clin Pharmacokinet       Date:  1976       Impact factor: 6.447

5.  Delayed clearance of diazepam due to cimetidine.

Authors:  U Klotz; I Reimann
Journal:  N Engl J Med       Date:  1980-05-01       Impact factor: 91.245

6.  Effects of cimetidine and absorption of tetracycline.

Authors:  M Garty; A Hurwitz
Journal:  Br J Clin Pharmacol       Date:  1980-10       Impact factor: 4.335

7.  Concurrent administration of cimetidine and enteric-coated prednisolone: effect on plasma levels of prednisolone.

Authors:  P J Morrison; H J Rogers; I D Bradbrook; C Parsons
Journal:  Br J Clin Pharmacol       Date:  1980-07       Impact factor: 4.335

8.  Cimetidine increases the action of warfarin in man [proceedings].

Authors:  A M Breckenridge; M Challiner; S Mossman; B K Park; M J Serlin; R G Sibeon; J R Williams; J M Willoughby
Journal:  Br J Clin Pharmacol       Date:  1979-10       Impact factor: 4.335

9.  A field trial of cimetidine as the sole oral antacid in obstetric anaesthesia.

Authors:  J R Johnston; W McCaughey; J Moore; J W Dundee
Journal:  Anaesthesia       Date:  1982-01       Impact factor: 6.955

10.  Elevation of steady-state diazepam levels by cimetidine.

Authors:  U Klotz; I Reimann
Journal:  Clin Pharmacol Ther       Date:  1981-10       Impact factor: 6.875
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  6 in total

Review 1.  Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Part II).

Authors:  K Lauritsen; L S Laursen; J Rask-Madsen
Journal:  Clin Pharmacokinet       Date:  1990-08       Impact factor: 6.447

Review 2.  Pharmacokinetics in anaesthesia.

Authors:  J A Moffat; B Milne
Journal:  Can Anaesth Soc J       Date:  1983-05

Review 3.  Pharmacokinetic interactions of cimetidine 1987.

Authors:  A Somogyi; M Muirhead
Journal:  Clin Pharmacokinet       Date:  1987-05       Impact factor: 6.447

Review 4.  Interactions and non-interactions with ranitidine.

Authors:  W Kirch; H Hoensch; H D Janisch
Journal:  Clin Pharmacokinet       Date:  1984 Nov-Dec       Impact factor: 6.447

5.  The effect of cimetidine on the single dose pharmacokinetics of oral clobazam and N-desmethylclobazam.

Authors:  T Pullar; D Edwards; J R Haigh; S Peaker; M P Feely
Journal:  Br J Clin Pharmacol       Date:  1987-03       Impact factor: 4.335

6.  Ranitidine influences the uptake of oral midazolam.

Authors:  R J Elwood; P J Hildebrand; J W Dundee; P S Collier
Journal:  Br J Clin Pharmacol       Date:  1983-06       Impact factor: 4.335
  6 in total

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