Literature DB >> 21589470

1-[5-(4-Meth-oxy-phen-yl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethanone.

Asghar Abbas, Safdar Hussain, Noureen Hafeez, Kong Mun Lo, Aurangzeb Hasan.   

Abstract

The title mol-ecule, C(18)H(18)N(2)O(2), is V-shaped with the pyrazoline moiety being inclined to the adjacent phenyl ring by an angle of 6.49 (9)°, while the 4-meth-oxy-substituted ring is inclined to the pyrazoline ring by 82.99 (9)°. In the crystal, adjacent mol-ecules are linked by C-H⋯O inter-actions, forming chains propagating in [100]. There are also C-H⋯π inter-actions involving adjacent mol-ecules and those related by an inversion center.

Entities:  

Year:  2010        PMID: 21589470      PMCID: PMC3011559          DOI: 10.1107/S1600536810045861

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN: 1600-5368


  11 in total

1.  A short history of SHELX.

Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

2.  Anticonvulsant activity and monoamine oxidase inhibitory properties of 1,3,5-trisubstituted pyrazolines.

Authors:  S S Parmar; B R Pandey; C Dwivedi; R D Harbison
Journal:  J Pharm Sci       Date:  1974-07       Impact factor: 3.534

3.  Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.

Authors:  Kotha Subbaramaiah; Larry Norton; William Gerald; Andrew J Dannenberg
Journal:  J Biol Chem       Date:  2002-03-18       Impact factor: 5.157

4.  1-{5-[4-(Hex-yloxy)phen-yl]-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl}ethanone.

Authors:  Asghar Abbas; Safdar Hussain; Noureen Hafeez; Kong Mun Lo; Aurangzeb Hasan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-04

5.  Novel immunosuppressive agents. Potent immunological activity of some bensothiopyrano [4,3-c]pyrazol-3-ones.

Authors:  J G Lombardino; I G Otterness
Journal:  J Med Chem       Date:  1981-07       Impact factor: 7.446

6.  Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 1. Quantitative structure-activity relationships vs. L1210 leukemia in mice.

Authors:  G J Hatheway; C Hansch; K H Kim; S R Milstein; C L Schmidt; R N Smith; F R Quinn
Journal:  J Med Chem       Date:  1978-06       Impact factor: 7.446

7.  Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide.

Authors:  I G Rathish; Kalim Javed; Shamim Ahmad; Sameena Bano; M S Alam; K K Pillai; Surender Singh; Vivek Bagchi
Journal:  Bioorg Med Chem Lett       Date:  2008-10-30       Impact factor: 2.823

8.  Tuning the photoinduced electron-transfer thermodynamics in 1,3,5-triaryl-2-pyrazoline fluorophores: X-ray structures, photophysical characterization, computational analysis, and in vivo evaluation.

Authors:  Christoph J Fahrni; Liuchun Yang; Donald G VanDerveer
Journal:  J Am Chem Soc       Date:  2003-04-02       Impact factor: 15.419

9.  4-[1-Acetyl-3-(4-methoxy-phen-yl)-2-pyrazolin-5-yl]phenol.

Authors:  Xue Bai; Hua-Feng Chen; Kuan Zhang; Ying Li; Shu-Fan Yin
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-10-28

10.  1-[5-(3,4-Dichlorophenyl)-3-(2-naphthyl)-4,5-dihydropyrazol-1-yl]ethanone.

Authors:  Zhi-Ke Lu; Shen Li; Yan Feng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-08-23
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.