Literature DB >> 2158943

Synthesis of 11C-labeled (+-)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imin e [(+-)-[11C]MK801].

D O Kiesewetter1, R D Finn, K C Rice, J A Monn.   

Abstract

The synthesis of C5 labeled (+-)-5-[11C]methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten- 5,10-imine [(+-)-[11C]MK801] has been accomplished via alkylation of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine-N-t- butylformamidine [(+-)-5-des-methyl MK801 formamidine). The 11C labeling is accomplished by reaction of the anion of (+-)-5-des-methyl MK801 formamidine, generated with s-butyllithium, and [11C]methyl iodide.

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Year:  1990        PMID： 2158943     DOI： 10.1016/0883-2889(90)90098-2

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum A        ISSN： 0883-2889


  3 in total

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Authors:  Gregory R Naumiec; Lisheng Cai; Victor W Pike
Journal:  Bioorg Med Chem Lett       Date:  2014-11-29       Impact factor: 2.823

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Authors:  Gregory R Naumiec; Kimberley J Jenko; Sami S Zoghbi; Robert B Innis; Lisheng Cai; Victor W Pike
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3.  In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization.

Authors:  Patrick Vandeputte; Françoise Ischer; Dominique Sanglard; Alix T Coste
Journal:  PLoS One       Date:  2011-10-31       Impact factor: 3.240
  3 in total

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