Literature DB >> 2158629

G0 is a major growth cone protein subject to regulation by GAP-43.

S M Strittmatter1, D Valenzuela, T E Kennedy, E J Neer, M C Fishman.   

Abstract

G0, a GTP-binding protein that transduces information from transmembrane receptors, has been found to be a major component of the neuronal growth cone membrane. GAP-43, an intracellular growth cone protein closely associated with neuronal growth, stimulates GTP-gamma-S binding to G0. It does so through an amino-terminal domain homologous to G-linked transmembrane receptors. Thus, G0 in the growth cone may be regulated by intracellular as well as extracellular signals.

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Year:  1990        PMID： 2158629     DOI： 10.1038/344836a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  87 in total

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10.  Palmitoylcarnitine affects localization of growth associated protein GAP-43 in plasma membrane subdomains and its interaction with Gα(o) in neuroblastoma NB-2a cells.

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