Literature DB >> 1314560

In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors.

T M Savarese1, C M Fraser.   

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Year:  1992        PMID: 1314560      PMCID: PMC1130983          DOI: 10.1042/bj2830001

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


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  171 in total

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2.  Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

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3.  cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

Authors:  B K Kobilka; R A Dixon; T Frielle; H G Dohlman; M A Bolanowski; I S Sigal; T L Yang-Feng; U Francke; M G Caron; R J Lefkowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

4.  Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence.

Authors:  T Kubo; A Maeda; K Sugimoto; I Akiba; A Mikami; H Takahashi; T Haga; K Haga; A Ichiyama; K Kangawa
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5.  Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains.

Authors:  D Young; G Waitches; C Birchmeier; O Fasano; M Wigler
Journal:  Cell       Date:  1986-06-06       Impact factor: 41.582

6.  Identification of a family of muscarinic acetylcholine receptor genes.

Authors:  T I Bonner; N J Buckley; A C Young; M R Brann
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7.  Chromosomal organization of adrenergic receptor genes.

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Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

8.  Molecular characterization of a rat alpha 2B-adrenergic receptor.

Authors:  D W Zeng; J K Harrison; D D D'Angelo; C M Barber; A L Tucker; Z H Lu; K R Lynch
Journal:  Proc Natl Acad Sci U S A       Date:  1990-04       Impact factor: 11.205

9.  Chimeric muscarinic cholinergic: beta-adrenergic receptors that activate Gs in response to muscarinic agonists.

Authors:  S K Wong; E M Parker; E M Ross
Journal:  J Biol Chem       Date:  1990-04-15       Impact factor: 5.157

10.  Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy.

Authors:  R Henderson; J M Baldwin; T A Ceska; F Zemlin; E Beckmann; K H Downing
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Review 1.  Structural organization of G-protein-coupled receptors.

Authors:  A L Lomize; I D Pogozheva; H I Mosberg
Journal:  J Comput Aided Mol Des       Date:  1999-07       Impact factor: 3.686

Review 2.  Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.

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5.  Exploration of the ligand binding site of the human 5-HT(4) receptor by site-directed mutagenesis and molecular modeling.

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6.  Expression cloning of an ATP receptor from mouse neuroblastoma cells.

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7.  Structure-activity analysis of synthetic alpha-thrombin-receptor-activating peptides.

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8.  G-Protein binding domains of the angiotensin II AT1A receptors mapped with synthetic peptides selected from the receptor sequence.

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9.  Pyrano[2,3,4-cd]indole as a Scaffold for Selective Nonbasic 5-HT6R Ligands.

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10.  Dependence of agonist activation on a conserved apolar residue in the third intracellular loop of the AT1 angiotensin receptor.

Authors:  L Hunyady; M Zhang; G Jagadeesh; M Bor; T Balla; K J Catt
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-17       Impact factor: 11.205

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