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Literature DB >> 2158156

Mechanism and evolution of the uncoupling protein of brown adipose tissue.

Abstract

The uncoupling protein found in mitochondria from thermogenic brown adipose tissue is structurally very similar to two other mitochondrial carrier proteins transporting ADP/ATP and phosphate, respectively. Similarities are also seen with the mechanism of these carriers, which are part of a family of H+/OH(-)-substrate anion co-transporters, further strengthening the evidence that the uncoupling protein has evolved from this family of mitochondrial carrier proteins.

Entities: Chemical

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Year: 1990 PMID： 2158156 DOI： 10.1016/0968-0004(90)90194-g

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

43 in total

1. A cell plate-specific callose synthase and its interaction with phragmoplastin.

Authors: Z Hong; A J Delauney; D P Verma
Journal: Plant Cell Date: 2001-04 Impact factor: 11.277

2. Associations between uncoupling protein 2, body composition, and resting energy expenditure in lean and obese African American, white, and Asian children.

Authors: J A Yanovski; A L Diament; K N Sovik; T T Nguyen; H Li; N G Sebring; C H Warden
Journal: Am J Clin Nutr Date: 2000-06 Impact factor: 7.045

Review 3. Classical and alternative components of the mitochondrial respiratory chain in pathogenic fungi as potential therapeutic targets.

Authors: Vicente de Paulo Martins; Taisa Magnani Dinamarco; Carlos Curti; Sérgio Akira Uyemura
Journal: J Bioenerg Biomembr Date: 2011-02 Impact factor: 2.945

Mechanism and evolution of the uncoupling protein of brown adipose tissue.

1. A cell plate-specific callose synthase and its interaction with phragmoplastin.

2. Associations between uncoupling protein 2, body composition, and resting energy expenditure in lean and obese African American, white, and Asian children.

Review 3. Classical and alternative components of the mitochondrial respiratory chain in pathogenic fungi as potential therapeutic targets.

4. Alternative translocation of protons and halide ions by bacteriorhodopsin.

5. A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.

Review 6. Electrophysiology of the inner mitochondrial membrane.

Review 7. The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP.

Review 8. The functions of cardiolipin in cellular metabolism-potential modifiers of the Barth syndrome phenotype.

Review 9. The polymorphisms of UCP1 genes associated with fat metabolism, obesity and diabetes.

10. Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function.