5-(2-Fur-yl)-3-methyl-1-(3-nitro-phen-yl)-4,5-dihydro-1H-pyrazole.

In the title compound, C(14)H(13)N(3)O(3), the pyrazoline ring assumes an envelope conformation with the furanyl-bearing C atom at the flap position. The dihedral angle between the furan and nitrobenzene rings is 84.40 (9)°. Weak inter-molecular C-H⋯O hydrogen bonding is present in the crystal structure.

Related literature

For applications of pyrazoline derivatives, see: Hatheway et al. (1978 ▶); Mahajan et al. (1991 ▶); Sobczak & Pawlaczyk (1998 ▶).

Experimental

Crystal data

C14H13N3O3

M = 271.27

Triclinic,

a = 6.2089 (2) Å

b = 7.8581 (3) Å

c = 14.3800 (4) Å

α = 105.764 (2)°

β = 97.054 (2)°

γ = 96.944 (2)°

V = 661.31 (4) Å3

Z = 2

Mo Kα radiation

μ = 0.10 mm−1

T = 296 K

0.31 × 0.15 × 0.10 mm

Data collection

Bruker SMART CCD area-detector diffractometer

Absorption correction: none

9707 measured reflections

2590 independent reflections

1778 reflections with I > 2σ(I)

R int = 0.036

Refinement

R[F 2 > 2σ(F 2)] = 0.044

wR(F 2) = 0.121

S = 1.10

2590 reflections

181 parameters

H-atom parameters constrained

Δρmax = 0.14 e Å−3

Δρmin = −0.21 e Å−3

Data collection: SMART (Bruker, 1998 ▶); cell refinement: SAINT (Bruker, 1998 ▶); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ▶); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008 ▶); molecular graphics: ORTEP-3 for Windows (Farrugia, 1997 ▶); software used to prepare material for publication: WinGX (Farrugia, 1999 ▶).

Crystal structure: contains datablocks global, I. DOI: 10.1107/S1600536809031419/xu2580sup1.cif

Structure factors: contains datablocks I. DOI: 10.1107/S1600536809031419/xu2580Isup2.hkl

Additional supplementary materials: crystallographic information; 3D view; checkCIF report

C14H13N3O3	Z = 2
Mr = 271.27	F(000) = 284
Triclinic, P1	Dx = 1.362 Mg m−3
Hall symbol: -P 1	Mo Kα radiation, λ = 0.71073 Å
a = 6.2089 (2) Å	Cell parameters from 1598 reflections
b = 7.8581 (3) Å	θ = 3.5–24.6°
c = 14.3800 (4) Å	µ = 0.10 mm−1
α = 105.764 (2)°	T = 296 K
β = 97.054 (2)°	Block, bronze
γ = 96.944 (2)°	0.31 × 0.15 × 0.10 mm
V = 661.31 (4) Å3

Bruker SMART CCD area-detector diffractometer	1778 reflections with I > 2σ(I)
Radiation source: fine-focus sealed tube	Rint = 0.036
graphite	θmax = 26.0°, θmin = 3.5°
ω scans	h = −7→7
9707 measured reflections	k = −8→9
2590 independent reflections	l = −17→17

Refinement on F2	Primary atom site location: structure-invariant direct methods
Least-squares matrix: full	Secondary atom site location: difference Fourier map
R[F2 > 2σ(F2)] = 0.044	Hydrogen site location: inferred from neighbouring sites
wR(F2) = 0.121	H-atom parameters constrained
S = 1.10	w = 1/[σ2(Fo2) + (0.0608P)2] where P = (Fo2 + 2Fc2)/3
2590 reflections	(Δ/σ)max = 0.003
181 parameters	Δρmax = 0.14 e Å−3
0 restraints	Δρmin = −0.20 e Å−3

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

	x	y	z	Uiso*/Ueq
O	0.36743 (18)	0.34679 (15)	0.90208 (8)	0.0586 (3)
N1	0.1661 (2)	0.62239 (17)	0.78604 (10)	0.0496 (4)
N2	0.2000 (2)	0.45740 (16)	0.72794 (10)	0.0491 (4)
C9	0.3755 (2)	0.4521 (2)	0.67745 (11)	0.0429 (4)
C14	0.5059 (2)	0.6102 (2)	0.67820 (11)	0.0460 (4)
H14A	0.4772	0.7211	0.7132	0.055*
C7	0.0168 (3)	0.5942 (2)	0.83623 (13)	0.0534 (4)
C10	0.4224 (3)	0.2892 (2)	0.62195 (12)	0.0546 (4)
H10A	0.3347	0.1826	0.6191	0.066*
C4	0.2531 (2)	0.2318 (2)	0.81601 (12)	0.0477 (4)
C13	0.6784 (2)	0.5987 (2)	0.62600 (12)	0.0514 (4)
N3	0.8105 (2)	0.7665 (2)	0.62761 (12)	0.0680 (5)
O1	0.9707 (2)	0.7615 (2)	0.58611 (11)	0.0934 (5)
C5	0.0941 (2)	0.3072 (2)	0.75855 (12)	0.0508 (4)
H5A	0.0138	0.2126	0.7010	0.061*
C12	0.7298 (3)	0.4395 (3)	0.57272 (12)	0.0611 (5)
H12A	0.8487	0.4365	0.5391	0.073*
C6	−0.0684 (3)	0.4007 (3)	0.81836 (14)	0.0615 (5)
H6A	−0.2166	0.3686	0.7817	0.074*
H6B	−0.0677	0.3706	0.8795	0.074*
C1	0.4967 (3)	0.2476 (3)	0.94299 (14)	0.0607 (5)
H1B	0.5924	0.2920	1.0022	0.073*
O2	0.7571 (3)	0.9062 (2)	0.67000 (14)	0.1046 (6)
C11	0.5976 (3)	0.2848 (3)	0.57136 (13)	0.0642 (5)
H11A	0.6270	0.1748	0.5355	0.077*
C3	0.3090 (3)	0.0707 (2)	0.80439 (14)	0.0660 (5)
H3A	0.2550	−0.0308	0.7518	0.079*
C2	0.4665 (3)	0.0818 (3)	0.88708 (14)	0.0673 (5)
H2A	0.5350	−0.0108	0.8992	0.081*
C8	−0.0654 (3)	0.7433 (3)	0.90245 (15)	0.0793 (6)
H8A	0.0141	0.8556	0.9019	0.119*
H8B	−0.0444	0.7329	0.9678	0.119*
H8C	−0.2191	0.7381	0.8806	0.119*

	U11	U22	U33	U12	U13	U23
O	0.0577 (7)	0.0535 (7)	0.0622 (8)	0.0133 (5)	0.0000 (6)	0.0156 (6)
N1	0.0513 (8)	0.0481 (8)	0.0555 (8)	0.0152 (6)	0.0159 (6)	0.0190 (7)
N2	0.0507 (7)	0.0414 (7)	0.0613 (9)	0.0090 (6)	0.0178 (6)	0.0206 (7)
C9	0.0443 (8)	0.0457 (9)	0.0417 (9)	0.0103 (7)	0.0050 (7)	0.0172 (7)
C14	0.0459 (8)	0.0467 (9)	0.0464 (9)	0.0077 (7)	0.0087 (7)	0.0147 (7)
C7	0.0454 (8)	0.0673 (11)	0.0568 (10)	0.0186 (8)	0.0109 (8)	0.0284 (9)
C10	0.0639 (10)	0.0459 (10)	0.0528 (10)	0.0079 (8)	0.0105 (8)	0.0125 (8)
C4	0.0474 (8)	0.0414 (9)	0.0544 (10)	0.0009 (7)	0.0061 (7)	0.0179 (8)
C13	0.0452 (9)	0.0591 (10)	0.0501 (10)	0.0017 (8)	0.0074 (7)	0.0191 (8)
N3	0.0584 (9)	0.0749 (12)	0.0685 (10)	−0.0040 (8)	0.0163 (8)	0.0210 (9)
O1	0.0729 (9)	0.1114 (12)	0.0966 (11)	−0.0083 (8)	0.0418 (8)	0.0290 (9)
C5	0.0440 (8)	0.0488 (9)	0.0621 (10)	−0.0003 (7)	0.0046 (7)	0.0256 (8)
C12	0.0591 (10)	0.0759 (13)	0.0516 (11)	0.0182 (9)	0.0200 (8)	0.0159 (9)
C6	0.0403 (8)	0.0813 (13)	0.0765 (12)	0.0102 (8)	0.0121 (8)	0.0440 (11)
C1	0.0531 (10)	0.0751 (13)	0.0613 (11)	0.0207 (9)	0.0076 (8)	0.0285 (10)
O2	0.0990 (12)	0.0602 (9)	0.1522 (16)	−0.0069 (8)	0.0581 (11)	0.0187 (10)
C11	0.0777 (12)	0.0602 (11)	0.0550 (11)	0.0230 (10)	0.0176 (10)	0.0093 (9)
C3	0.0813 (13)	0.0457 (10)	0.0690 (13)	0.0129 (9)	0.0027 (10)	0.0164 (9)
C2	0.0761 (12)	0.0621 (13)	0.0761 (13)	0.0288 (10)	0.0118 (10)	0.0333 (11)
C8	0.0778 (13)	0.0996 (16)	0.0771 (14)	0.0422 (12)	0.0352 (11)	0.0316 (12)

O—C4	1.3689 (18)	N3—O2	1.208 (2)
O—C1	1.372 (2)	N3—O1	1.2209 (19)
N1—C7	1.277 (2)	C5—C6	1.532 (2)
N1—N2	1.3940 (18)	C5—H5A	0.9800
N2—C9	1.3803 (19)	C12—C11	1.376 (3)
N2—C5	1.4784 (19)	C12—H12A	0.9300
C9—C14	1.396 (2)	C6—H6A	0.9700
C9—C10	1.397 (2)	C6—H6B	0.9700
C14—C13	1.379 (2)	C1—C2	1.309 (2)
C14—H14A	0.9300	C1—H1B	0.9300
C7—C8	1.482 (2)	C11—H11A	0.9300
C7—C6	1.489 (3)	C3—C2	1.420 (2)
C10—C11	1.380 (2)	C3—H3A	0.9300
C10—H10A	0.9300	C2—H2A	0.9300
C4—C3	1.325 (2)	C8—H8A	0.9600
C4—C5	1.488 (2)	C8—H8B	0.9600
C13—C12	1.375 (2)	C8—H8C	0.9600
C13—N3	1.459 (2)
C4—O—C1	105.97 (13)	C4—C5—H5A	110.0
C7—N1—N2	108.34 (13)	C6—C5—H5A	110.0
C9—N2—N1	118.80 (12)	C13—C12—C11	117.03 (16)
C9—N2—C5	125.31 (13)	C13—C12—H12A	121.5
N1—N2—C5	111.64 (12)	C11—C12—H12A	121.5
N2—C9—C14	120.55 (14)	C7—C6—C5	103.00 (13)
N2—C9—C10	120.96 (14)	C7—C6—H6A	111.2
C14—C9—C10	118.47 (14)	C5—C6—H6A	111.2
C13—C14—C9	118.59 (15)	C7—C6—H6B	111.2
C13—C14—H14A	120.7	C5—C6—H6B	111.2
C9—C14—H14A	120.7	H6A—C6—H6B	109.1
N1—C7—C8	121.87 (16)	C2—C1—O	110.60 (15)
N1—C7—C6	113.46 (15)	C2—C1—H1B	124.7
C8—C7—C6	124.64 (16)	O—C1—H1B	124.7
C11—C10—C9	120.67 (16)	C12—C11—C10	121.50 (17)
C11—C10—H10A	119.7	C12—C11—H11A	119.3
C9—C10—H10A	119.7	C10—C11—H11A	119.3
C3—C4—O	109.50 (15)	C4—C3—C2	107.27 (16)
C3—C4—C5	134.10 (17)	C4—C3—H3A	126.4
O—C4—C5	116.37 (14)	C2—C3—H3A	126.4
C12—C13—C14	123.72 (16)	C1—C2—C3	106.65 (16)
C12—C13—N3	119.04 (15)	C1—C2—H2A	126.7
C14—C13—N3	117.24 (15)	C3—C2—H2A	126.7
O2—N3—O1	122.13 (17)	C7—C8—H8A	109.5
O2—N3—C13	118.76 (15)	C7—C8—H8B	109.5
O1—N3—C13	119.11 (17)	H8A—C8—H8B	109.5
N2—C5—C4	112.93 (12)	C7—C8—H8C	109.5
N2—C5—C6	100.18 (13)	H8A—C8—H8C	109.5
C4—C5—C6	113.50 (14)	H8B—C8—H8C	109.5
N2—C5—H5A	110.0

D—H···A	D—H	H···A	D···A	D—H···A
C12—H12A···O1i	0.93	2.51	3.311 (2)	144

Table 1

Hydrogen-bond geometry (Å, °)

D—H⋯A	D—H	H⋯A	D⋯A	D—H⋯A
C12—H12A⋯O1i	0.93	2.51	3.311 (2)	144

Symmetry code: (i) .