| Literature DB >> 2157695 |
N Naruse1, O Tenmyo, S Kobaru, H Kamei, T Miyaki, M Konishi, T Oki.
Abstract
New antibiotic pumilacidins A, B, C, D, E, F and G were isolated from the culture broth of a strain of Bacillus pumilus. They are cyclic acylheptapeptide composed of a beta-hydroxy fatty acid, two L-leucine, two D-leucine, L-glutamic acid, L-aspartic acid and L-isoleucine (or L-valine). Pumilacidin components were inhibitory to herpes simplex virus type 1 and H+, K(+)-ATPase and demonstrated antiulcer activity in rat.Entities:
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Year: 1990 PMID: 2157695 DOI: 10.7164/antibiotics.43.267
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649