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Literature DB >> 21571996

Scc1 (CP0432) and Scc4 (CP0033) function as a type III secretion chaperone for CopN of Chlamydia pneumoniae.

Eugenia Silva-Herzog¹, Sabrina S Joseph, Ann K Avery, Jose A Coba, Katerina Wolf, Kenneth A Fields, Gregory V Plano.

Abstract

The Chlamydia pneumoniae CopN protein is a member of the YopN/TyeA/InvE/MxiC family of secreted proteins that function to regulate the secretion of type III secretion system (T3SS) translocator and effector proteins. In this study, the Scc1 (CP0432) and Scc4 (CP0033) proteins of C. pneumoniae AR-39 were demonstrated to function together as a type III secretion chaperone that binds to an N-terminal region of CopN. The Scc1/Scc4 chaperone promoted the efficient secretion of CopN via a heterologous T3SS, whereas, the Scc3 chaperone, which binds to a C-terminal region of CopN, reduced CopN secretion.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2011 PMID： 21571996 PMCID： PMC3133303 DOI： 10.1128/JB.00203-11

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

41 in total

Review 1. Type III secretion: more systems than you think.

Authors: Paul Troisfontaines; Guy R Cornelis
Journal: Physiology (Bethesda) Date: 2005-10

2. Selection and characterization of Yersinia pestis YopN mutants that constitutively block Yop secretion.

Authors: Franco Ferracci; Florian D Schubot; David S Waugh; Gregory V Plano
Journal: Mol Microbiol Date: 2005-08 Impact factor: 3.501

Review 3. Protein delivery into eukaryotic cells by type III secretion machines.

Authors: Jorge E Galán; Hans Wolf-Watz
Journal: Nature Date: 2006-11-30 Impact factor: 49.962

4. Characterization of a Type III secretion substrate specificity switch (T3S4) domain in YscP from Yersinia enterocolitica.

Authors: Céline Agrain; Isabelle Callebaut; Laure Journet; Isabel Sorg; Cécile Paroz; Luís Jaime Mota; Guy R Cornelis
Journal: Mol Microbiol Date: 2005-04 Impact factor: 3.501

5. Calcium-regulated type III secretion of Yop proteins by an Escherichia coli hha mutant carrying a Yersinia pestis pCD1 virulence plasmid.

Authors: Sara Schesser Bartra; Michael W Jackson; Julia A Ross; Gregory V Plano
Journal: Infect Immun Date: 2006-02 Impact factor: 3.441

6. The ATP-dependent ClpXP and Lon proteases regulate expression of the Yersinia pestis type III secretion system via regulated proteolysis of YmoA, a small histone-like protein.

Authors: Michael W Jackson; Eugenia Silva-Herzog; Gregory V Plano
Journal: Mol Microbiol Date: 2004-12 Impact factor: 3.501

7. Interaction between components of the type III secretion system of Chlamydiaceae.

Authors: Anatoly Slepenkin; Luis M de la Maza; Ellena M Peterson
Journal: J Bacteriol Date: 2005-01 Impact factor: 3.490

8. Induction of type III secretion by cell-free Chlamydia trachomatis elementary bodies.

Authors: Wendy P Jamison; Ted Hackstadt
Journal: Microb Pathog Date: 2008-10-17 Impact factor: 3.738

9. The essential role of the CopN protein in Chlamydia pneumoniae intracellular growth.

Authors: Jin Huang; Cammie F Lesser; Stephen Lory
Journal: Nature Date: 2008-10-01 Impact factor: 49.962

10. Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretion.

Authors: Mark J Pallen; Scott A Beatson; Christopher M Bailey
Journal: BMC Microbiol Date: 2005-03-09 Impact factor: 3.605

21 in total

1. Regulation of Type III Secretion of Translocon and Effector Proteins by the EsaB/EsaL/EsaM Complex in Edwardsiella tarda.

Authors: Lu Yi Liu; Pin Nie; Hong Bing Yu; Hai Xia Xie
Journal: Infect Immun Date: 2017-08-18 Impact factor: 3.441

Review 2. New frontiers in type III secretion biology: the Chlamydia perspective.

Authors: K E Mueller; G V Plano; K A Fields
Journal: Infect Immun Date: 2013-10-14 Impact factor: 3.441

3. Insight into microtubule nucleation from tubulin-capping proteins.

Authors: Valérie Campanacci; Agathe Urvoas; Soraya Cantos-Fernandes; Magali Aumont-Nicaise; Ana-Andreea Arteni; Christophe Velours; Marie Valerio-Lepiniec; Birgit Dreier; Andreas Plückthun; Antoine Pilon; Christian Poüs; Philippe Minard; Benoît Gigant
Journal: Proc Natl Acad Sci U S A Date: 2019-04-29 Impact factor: 11.205

Review 4. A working model for the type III secretion mechanism in Chlamydia.

Authors: Joshua C Ferrell; Kenneth A Fields
Journal: Microbes Infect Date: 2015-10-26 Impact factor: 2.700

5. Context-Dependent Action of Scc4 Reinforces Control of the Type III Secretion System.

Authors: Leiqiong Gao; Yanguang Cong; Gregory V Plano; Xiancai Rao; Lyndsey N Gisclair; Sara Schesser Bartra; Megan A Macnaughtan; Li Shen
Journal: J Bacteriol Date: 2020-07-09 Impact factor: 3.490

6. Multipart Chaperone-Effector Recognition in the Type III Secretion System of Chlamydia trachomatis.

Authors: Li Shen; Megan A Macnaughtan; Kyla M Frohlich; Yanguang Cong; Octavia Y Goodwin; Chau-wen Chou; Louis LeCour; Kristen Krup; Miao Luo; David K Worthylake
Journal: J Biol Chem Date: 2015-10-05 Impact factor: 5.157

7. Hierarchical protein targeting and secretion is controlled by an affinity switch in the type III secretion system of enteropathogenic Escherichia coli.

Authors: Athina G Portaliou; Konstantinos C Tsolis; Maria S Loos; Vassileia Balabanidou; Josep Rayo; Alexandra Tsirigotaki; Valerie F Crepin; Gad Frankel; Charalampos G Kalodimos; Spyridoula Karamanou; Anastassios Economou
Journal: EMBO J Date: 2017-11-06 Impact factor: 11.598