| Literature DB >> 215712 |
K Dörries, R T Johnson, V ter Meulen.
Abstract
The human papova (JC) virus was extracted from brain of a patient with progressive multifocal leukoencephalopathy. A single band of virus was obtained at a density of 1.345 g/ml CsCl.JC virus DNA was purified and a highly specific cRNA was generated in vitro. In situ hybridization with JC virus cRNA and autoradiography on sections of the same brain revealed silver grains over oligodendrocytes, astrocytes and possible vascular endothelial cells, indicating the presence of JC virus DNA in these different cell classes.Entities:
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Year: 1979 PMID： 215712 DOI： 10.1099/0022-1317-42-1-49
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891