Literature DB >> 21566260

Interference between PARPs and SIRT1: a novel approach to healthy ageing?

Carles Cantó1, Johan Auwerx.   

Abstract

Poly(ADP-ribosyl) polymerases (PARPs) have traditionally been linked to chromosome maintenance and DNA repair. Recent findings identify PARPs as key modulators of metabolism through their influence on SIRT1 activity, hinting to a possible role of PARPs as longevity regulators.

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Year:  2011        PMID： 21566260      PMCID： PMC3156604          DOI： 10.18632/aging.100326

Source DB:  PubMed          Journal:  Aging (Albany NY)        ISSN： 1945-4589            Impact factor:   5.682


  32 in total

Review 1.  Sir2 links chromatin silencing, metabolism, and aging.

Authors:  L Guarente
Journal:  Genes Dev       Date:  2000-05-01       Impact factor: 11.361

2.  Nicotinamide mononucleotide activation of new DNA-dependent polyadenylic acid synthesizing nuclear enzyme.

Authors:  P CHAMBON; J D WEILL; P MANDEL
Journal:  Biochem Biophys Res Commun       Date:  1963-04-02       Impact factor: 3.575

3.  Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells.

Authors:  J M de Murcia; C Niedergang; C Trucco; M Ricoul; B Dutrillaux; M Mark; F J Oliver; M Masson; A Dierich; M LeMeur; C Walztinger; P Chambon; G de Murcia
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-08       Impact factor: 11.205

4.  PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase.

Authors:  J C Amé; V Rolli; V Schreiber; C Niedergang; F Apiou; P Decker; S Muller; T Höger; J Ménissier-de Murcia; G de Murcia
Journal:  J Biol Chem       Date:  1999-06-18       Impact factor: 5.157

5.  Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1.

Authors:  Kevin J Bitterman; Rozalyn M Anderson; Haim Y Cohen; Magda Latorre-Esteves; David A Sinclair
Journal:  J Biol Chem       Date:  2002-09-23       Impact factor: 5.157

6.  PARP-2 regulates SIRT1 expression and whole-body energy expenditure.

Authors:  Péter Bai; Carles Canto; Attila Brunyánszki; Aline Huber; Magdolna Szántó; Yana Cen; Hiroyasu Yamamoto; Sander M Houten; Borbala Kiss; Hugues Oudart; Pál Gergely; Josiane Menissier-de Murcia; Valérie Schreiber; Anthony A Sauve; Johan Auwerx
Journal:  Cell Metab       Date:  2011-04-06       Impact factor: 27.287

Review 7.  The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.

Authors:  Riekelt H Houtkooper; Carles Cantó; Ronald J Wanders; Johan Auwerx
Journal:  Endocr Rev       Date:  2009-12-09       Impact factor: 19.871

8.  H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion.

Authors:  Ayako Furukawa; Saeko Tada-Oikawa; Shosuke Kawanishi; Shinji Oikawa
Journal:  Cell Physiol Biochem       Date:  2007

9.  Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span.

Authors:  K Grube; A Bürkle
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

10.  PARP is involved in replicative aging in Neurospora crassa.

Authors:  Gregory O Kothe; Maki Kitamura; Mitsuko Masutani; Eric U Selker; Hirokazu Inoue
Journal:  Fungal Genet Biol       Date:  2010-01-04       Impact factor: 3.495
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  22 in total

1.  Resveratrol activates SIRT1 in a Lamin A-dependent manner.

Authors:  Shrestha Ghosh; Baohua Liu; Zhongjun Zhou
Journal:  Cell Cycle       Date:  2013-02-25       Impact factor: 4.534

Review 2.  Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?

Authors:  Carles Cantó; Johan Auwerx
Journal:  Pharmacol Rev       Date:  2011-11-21       Impact factor: 25.468

3.  Suppression of ERR targets by a PPARα/Sirt1 complex in the failing heart.

Authors:  Shin-ichi Oka; Peiyong Zhai; Ralph Alcendor; Ji Yeon Park; Bin Tian; Junichi Sadoshima
Journal:  Cell Cycle       Date:  2012-03-01       Impact factor: 4.534

Review 4.  Role of endothelial NAD+ deficiency in age-related vascular dysfunction.

Authors:  Anna Csiszar; Stefano Tarantini; Andriy Yabluchanskiy; Priya Balasubramanian; Tamas Kiss; Eszter Farkas; Joseph A Baur; Zoltan Ungvari
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-03-15       Impact factor: 4.733

5.  Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi.

Authors:  Sue-Jie Koo; Imran H Chowdhury; Bartosz Szczesny; Xianxiu Wan; Nisha J Garg
Journal:  Infect Immun       Date:  2016-11-18       Impact factor: 3.441

6.  The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans.

Authors:  Catherine Neumann; Jessica Baesler; Gereon Steffen; Merle Marie Nicolai; Tabea Zubel; Michael Aschner; Alexander Bürkle; Aswin Mangerich; Tanja Schwerdtle; Julia Bornhorst
Journal:  J Trace Elem Med Biol       Date:  2019-09-14       Impact factor: 3.849

7.  Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents.

Authors:  Javier A Menendez; Jorge Joven; Gerard Aragonès; Enrique Barrajón-Catalán; Raúl Beltrán-Debón; Isabel Borrás-Linares; Jordi Camps; Bruna Corominas-Faja; Sílvia Cufí; Salvador Fernández-Arroyo; Anabel Garcia-Heredia; Anna Hernández-Aguilera; María Herranz-López; Cecilia Jiménez-Sánchez; Eugeni López-Bonet; Jesús Lozano-Sánchez; Fedra Luciano-Mateo; Begoña Martin-Castillo; Vicente Martin-Paredero; Almudena Pérez-Sánchez; Cristina Oliveras-Ferraros; Marta Riera-Borrull; Esther Rodríguez-Gallego; Rosa Quirantes-Piné; Anna Rull; Laura Tomás-Menor; Alejandro Vazquez-Martin; Carlos Alonso-Villaverde; Vicente Micol; Antonio Segura-Carretero
Journal:  Cell Cycle       Date:  2013-01-31       Impact factor: 4.534

Review 8.  Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.

Authors:  Carles Cantó; Anthony A Sauve; Peter Bai
Journal:  Mol Aspects Med       Date:  2013-01-25

Review 9.  NAD+ as a signaling molecule modulating metabolism.

Authors:  C Cantó; J Auwerx
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2012-02-17

10.  Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human Disease.

Authors:  Scott H Greenwald; Jeremy R Charette; Magdalena Staniszewska; Lan Ying Shi; Steve D M Brown; Lisa Stone; Qin Liu; Wanda L Hicks; Gayle B Collin; Michael R Bowl; Mark P Krebs; Patsy M Nishina; Eric A Pierce
Journal:  Am J Pathol       Date:  2016-05-18       Impact factor: 4.307
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