OBJECTIVE: The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the likelihood of remission and recurrence of PTSD. METHOD: The SCID I was administered to 290 borderline in-patients and 72 axis II comparison subjects during their index admission and re-administered at five contiguous 2-year follow-up periods. RESULTS: The prevalence of PTSD declined significantly over time for patients with borderline personality (BPD) (61%). Over 85% of borderline patients meeting criteria for PTSD at baseline experienced a remission by the time of the 10-year follow-up. Recurrences (40%) and new onsets (27%) were less common. A childhood history of sexual abuse significantly decreased the likelihood of remission from PTSD, and an adult history of sexual assault significantly increased the likelihood of a recurrence of PTSD. CONCLUSION: Taken together, the results of this study suggest that PTSD is not a chronic disorder for the majority of borderline patients. They also suggest a strong relationship between sexual adversity and the course of PTSD among patients with BPD.
OBJECTIVE: The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the likelihood of remission and recurrence of PTSD. METHOD: The SCID I was administered to 290 borderline in-patients and 72 axis II comparison subjects during their index admission and re-administered at five contiguous 2-year follow-up periods. RESULTS: The prevalence of PTSD declined significantly over time for patients with borderline personality (BPD) (61%). Over 85% of borderline patients meeting criteria for PTSD at baseline experienced a remission by the time of the 10-year follow-up. Recurrences (40%) and new onsets (27%) were less common. A childhood history of sexual abuse significantly decreased the likelihood of remission from PTSD, and an adult history of sexual assault significantly increased the likelihood of a recurrence of PTSD. CONCLUSION: Taken together, the results of this study suggest that PTSD is not a chronic disorder for the majority of borderline patients. They also suggest a strong relationship between sexual adversity and the course of PTSD among patients with BPD.
Authors: M C Zanarini; A A Williams; R E Lewis; R B Reich; S C Vera; M F Marino; A Levin; L Yong; F R Frankenburg Journal: Am J Psychiatry Date: 1997-08 Impact factor: 18.112
Authors: Julia A Golier; Rachel Yehuda; Linda M Bierer; Vivian Mitropoulou; Antonia S New; James Schmeidler; Jeremy M Silverman; Larry J Siever Journal: Am J Psychiatry Date: 2003-11 Impact factor: 18.112
Authors: Caron Zlotnick; Benjamin F Rodriguez; Risa B Weisberg; Steven E Bruce; Michael A Spencer; Larry Culpepper; Martin B Keller Journal: J Nerv Ment Dis Date: 2004-02 Impact factor: 2.254
Authors: Shirley Yen; M Tracie Shea; Cynthia L Battle; Dawn M Johnson; Caron Zlotnick; Regina Dolan-Sewell; Andrew E Skodol; Carlos M Grilo; John G Gunderson; Charles A Sanislow; Mary C Zanarini; Donna S Bender; Jennifer Bame Rettew; Thomas H McGlashan Journal: J Nerv Ment Dis Date: 2002-08 Impact factor: 2.254