Literature DB >> 21552470

Compton Scattering in Clinical PET/CT With High Resolution Half Ring PET Insert Device.

Sergey A Komarov1, Heyu Wu, Daniel B Keesing, Joseph A O'Sullivan, Yuan-Chuan Tai.   

Abstract

The integration of a high resolution PET insert into a conventional PET system can significantly improve the resolution and the contrast of its images within a reduced imaging field of view. For the rest of the scanner imaging field of view, the insert is a highly attenuating and scattering media. In order to use all available coincidence events (including coincidences between 2 detectors in the original scanner, namely the scanner-scanner coincidences), appropriate scatter and attenuation corrections have to be implemented. In this work, we conducted a series of Monte Carlo simulations to estimate the composition of the scattering background and the importance of the scatter correction. We implemented and tested the Single Scatter Simulation (SSS) algorithm for a hypothetical system and show good agreement between the estimated scatter using SSS and Monte Carlo simulated scatter contribution. We further applied the SSS to estimate scatter contribution from an existing prototype PET insert for a clinical PET/CT scanner. The results demonstrated the applicability of SSS to estimate the scatter contribution within a clinical PET/CT system even when there is a high resolution half ring PET insert device in its imaging field of view.

Entities:  

Year:  2010        PMID: 21552470      PMCID: PMC3087385          DOI: 10.1109/TNS.2010.2046754

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  3 in total

1.  Virtual-pinhole PET.

Authors:  Yuan-Chuan Tai; Heyu Wu; Debashish Pal; Joseph A O'Sullivan
Journal:  J Nucl Med       Date:  2008-02-20       Impact factor: 10.057

2.  A feasibility study of a prototype PET insert device to convert a general-purpose animal PET scanner to higher resolution.

Authors:  Heyu Wu; Debashish Pal; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  J Nucl Med       Date:  2007-12-12       Impact factor: 10.057

3.  Micro insert: a prototype full-ring PET device for improving the image resolution of a small-animal PET scanner.

Authors:  Heyu Wu; Debashish Pal; Tae Yong Song; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  J Nucl Med       Date:  2008-09-15       Impact factor: 10.057

  3 in total
  5 in total

1.  A generalized reconstruction framework for unconventional PET systems.

Authors:  Aswin John Mathews; Ke Li; Sergey Komarov; Qiang Wang; Bosky Ravindranath; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  Med Phys       Date:  2015-08       Impact factor: 4.071

2.  Improving PET imaging for breast cancer using virtual pinhole PET half-ring insert.

Authors:  Aswin John Mathews; Sergey Komarov; Heyu Wu; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  Phys Med Biol       Date:  2013-09-02       Impact factor: 3.609

3.  Parallel Beam Approximation for Calculation of Detection Efficiency of Crystals in PET Detector Arrays.

Authors:  Sergey Komarov; Tae Yong Song; Heyu Wu; Yuan-Chuan Tai
Journal:  IEEE Trans Nucl Sci       Date:  2011-10       Impact factor: 1.679

4.  Image reconstruction and system modeling techniques for virtual-pinhole PET insert systems.

Authors:  Daniel B Keesing; Aswin Mathews; Sergey Komarov; Heyu Wu; Tae Yong Song; Joseph A O'Sullivan; Yuan-Chuan Tai
Journal:  Phys Med Biol       Date:  2012-04-11       Impact factor: 3.609

5.  Investigation of the limitations of the highly pixilated CdZnTe detector for PET applications.

Authors:  Sergey Komarov; Yongzhi Yin; Heyu Wu; Jie Wen; Henric Krawczynski; Ling-Jian Meng; Yuan-Chuan Tai
Journal:  Phys Med Biol       Date:  2012-10-18       Impact factor: 3.609

  5 in total

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