Literature DB >> 21541737

[Treatment strategies for chronic total occlusion: current status and outlook].

G S Werner1.   

Abstract

The present article discusses the current status of treatment strategies for chronic total occlusion (CTO) and the prospects offered by new therapies. The indication for revascularisation recognized in the current European guidelines includes the presence of typical symptoms and evidence of ischemia of over 10% of the total myocardium, while in patients with multiple vascular diseases the aim is complete revascularisation. Although the vast majority of patients with CTO fulfil these criteria, they are currently not receiving interventional treatment as frequently as expected. The reasons often given for this include the low success rates and high recurrence rates. However, both problems have been improved by drug-eluting stents (DES) on the one hand and by wire techniques and strategies on the other, such that results almost comparable with non-occluded coronary lesions can be achieved. While more advanced approaches like retrograde recanalization should be restricted to specialized centres, marked improvements can be achieved even without these special techniques by means of consistent further training and the application of modern techniques. Despite the aggressiveness of these approaches to pass through an occluded artery, the complication rate is not higher than with non-occluded lesions when the specific complications of recanalization are avoided in a careful approach. Further technical improvements are expected with the use of modern imaging techniques such as intravascular ultrasound and high-resolution CT imaging of coronary arteries.

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Year:  2011        PMID: 21541737     DOI: 10.1007/s00059-011-3461-4

Source DB:  PubMed          Journal:  Herz        ISSN: 0340-9937            Impact factor:   1.443


  47 in total

1.  Coronary artery perforation during percutaneous intervention: incidence and outcome.

Authors:  M G Gunning; I L Williams; D E Jewitt; A M Shah; R J Wainwright; M R Thomas
Journal:  Heart       Date:  2002-11       Impact factor: 5.994

2.  The BridgePoint devices to facilitate recanalization of chronic total coronary occlusions through controlled subintimal reentry.

Authors:  Gerald S Werner
Journal:  Expert Rev Med Devices       Date:  2011-01       Impact factor: 3.166

3.  Anchoring technique to improve guiding catheter support in coronary angioplasty of chronic total occlusions.

Authors:  Mitsugu Hirokami; Shigeru Saito; Harutatsu Muto
Journal:  Catheter Cardiovasc Interv       Date:  2006-03       Impact factor: 2.692

4.  European perspective in the recanalisation of Chronic Total Occlusions (CTO): consensus document from the EuroCTO Club.

Authors:  Carlo Di Mario; Gerald S Werner; Georgios Sianos; Alfredo R Galassi; Joachim Büttner; Dariusz Dudek; Bernard Chevalier; Thierry Lefevre; Joachim Schofer; Jacques Koolen; Horst Sievert; Bernhard Reimers; Jean Fajadet; Antonio Colombo; Anthony Gershlick; Patrick W Serruys; Nicolaus Reifart
Journal:  EuroIntervention       Date:  2007-05       Impact factor: 6.534

5.  Paclitaxel-eluting stents for the treatment of chronic total coronary occlusions: a strategy of extensive lesion coverage with drug-eluting stents.

Authors:  Gerald S Werner; Gero Schwarz; Dirk Prochnau; Michael Fritzenwanger; Andreas Krack; Stefan Betge; Hans R Figulla
Journal:  Catheter Cardiovasc Interv       Date:  2006-01       Impact factor: 2.692

6.  Recent trends in the percutaneous treatment of chronic total coronary occlusions.

Authors:  J Dawn Abbott; Kevin E Kip; Helen A Vlachos; Neil Sawhney; Vankeepuran S Srinivas; Alice K Jacobs; David R Holmes; David O Williams
Journal:  Am J Cardiol       Date:  2006-04-21       Impact factor: 2.778

7.  Prevention of lesion recurrence in chronic total coronary occlusions by paclitaxel-eluting stents.

Authors:  Gerald S Werner; Andreas Krack; Gero Schwarz; Dirk Prochnau; Stefan Betge; Hans R Figulla
Journal:  J Am Coll Cardiol       Date:  2004-12-21       Impact factor: 24.094

8.  The functional reserve of collaterals supplying long-term chronic total coronary occlusions in patients without prior myocardial infarction.

Authors:  Gerald S Werner; Ralf Surber; Markus Ferrari; Michael Fritzenwanger; Hans R Figulla
Journal:  Eur Heart J       Date:  2006-09-26       Impact factor: 29.983

9.  The ratio of contrast volume to glomerular filtration rate predicts outcomes after percutaneous coronary intervention for ST-segment elevation acute myocardial infarction.

Authors:  Aviv Mager; Hana Vaknin Assa; Eli I Lev; Tamir Bental; Abid Assali; Ran Kornowski
Journal:  Catheter Cardiovasc Interv       Date:  2010-10-14       Impact factor: 2.692

10.  Improvement in survival following successful percutaneous coronary intervention of coronary chronic total occlusions: variability by target vessel.

Authors:  David M Safley; John A House; Steven P Marso; J Aaron Grantham; Barry D Rutherford
Journal:  JACC Cardiovasc Interv       Date:  2008-06       Impact factor: 11.195

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  2 in total

Review 1.  Chronic total coronary occlusion recanalization: Current techniques and new devices.

Authors:  Jan-Erik Gülker; Lars Bansemir; Heinrich G Klues; Alexander Bufe
Journal:  J Saudi Heart Assoc       Date:  2016-08-20

2.  A comparison of procedural success rate and long-term clinical outcomes between in-stent restenosis chronic total occlusion and de novo chronic total occlusion using multicenter registry data.

Authors:  Seung Hun Lee; Jae Young Cho; Je Sang Kim; Hyun Jong Lee; Jeong Hoon Yang; Jae Hyoung Park; Soon Jun Hong; Rak Kyeong Choi; Seung-Hyuk Choi; Hyeon-Cheol Gwon; Do-Sun Lim; Cheol Woong Yu
Journal:  Clin Res Cardiol       Date:  2019-09-24       Impact factor: 5.460

  2 in total

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