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Literature DB >> 21540846

Emerging models and paradigms for stem cell ageing.

Abstract

Ageing is accompanied by a progressive decline in stem cell function, resulting in less effective tissue homeostasis and repair. Here we discuss emerging invertebrate models that provide insights into molecular pathways of age-related stem cell dysfunction in mammals, and we present various paradigms of how stem cell functionality changes with age, including impaired self-renewal and aberrant differentiation potential.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21540846 PMCID： PMC3257978 DOI： 10.1038/ncb0511-506

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

111 in total

1. Life span of individual yeast cells.

Authors: R K MORTIMER; J R JOHNSTON
Journal: Nature Date: 1959-06-20 Impact factor: 49.962

Review 2. The effects of aging on stem cell behavior in Drosophila.

Authors: Lei Wang; D Leanne Jones
Journal: Exp Gerontol Date: 2010-10-30 Impact factor: 4.032

3. Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice.

Authors: Zhangfa Song; Jianwei Wang; Luis Miguel Guachalla; Grzegorz Terszowski; Hans-Reimer Rodewald; Zhenyu Ju; K Lenhard Rudolph
Journal: Blood Date: 2009-12-02 Impact factor: 22.113

Review 4. Epigenetic regulation of aging stem cells.

Authors: E A Pollina; A Brunet
Journal: Oncogene Date: 2011-03-28 Impact factor: 9.867

Review 5. Stem cells and the niche: a dynamic duo.

Authors: Justin Voog; D Leanne Jones
Journal: Cell Stem Cell Date: 2010-02-05 Impact factor: 24.633

6. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

Authors: Grant A Challen; Nathan C Boles; Stuart M Chambers; Margaret A Goodell
Journal: Cell Stem Cell Date: 2010-03-05 Impact factor: 24.633

7. The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila.

Authors: Joung-Sun Park; Young-Shin Kim; Mi-Ae Yoo
Journal: Aging (Albany NY) Date: 2009-05-21 Impact factor: 5.682

Review 8. Manifestations and mechanisms of stem cell aging.

Authors: Ling Liu; Thomas A Rando
Journal: J Cell Biol Date: 2011-04-18 Impact factor: 10.539

9. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster.

Authors: Ivana Bjedov; Janne M Toivonen; Fiona Kerr; Cathy Slack; Jake Jacobson; Andrea Foley; Linda Partridge
Journal: Cell Metab Date: 2010-01 Impact factor: 27.287

10. Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses.

Authors: Morgan E Carlson; Michael J Conboy; Michael Hsu; Laurel Barchas; Jaemin Jeong; Anshu Agrawal; Amanda J Mikels; Smita Agrawal; David V Schaffer; Irina M Conboy
Journal: Aging Cell Date: 2009-09-02 Impact factor: 9.304

100 in total

1. The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche.

Authors: Hila Toledano; Cecilia D'Alterio; Benjamin Czech; Erel Levine; D Leanne Jones
Journal: Nature Date: 2012-05-23 Impact factor: 49.962

2. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group.

Authors: Kevin P High; Mark Brennan-Ing; David B Clifford; Mardge H Cohen; Judith Currier; Steven G Deeks; Sherry Deren; Rita B Effros; Kelly Gebo; Jörg J Goronzy; Amy C Justice; Alan Landay; Jules Levin; Paolo G Miotti; Robert J Munk; Heidi Nass; Charles R Rinaldo; Michael G Shlipak; Russell Tracy; Victor Valcour; David E Vance; Jeremy D Walston; Paul Volberding
Journal: J Acquir Immune Defic Syndr Date: 2012-07-01 Impact factor: 3.731

3. Stem cells and aging: a chicken-or-the-egg issue?

Authors: Johanna A Smith; René Daniel
Journal: Aging Dis Date: 2012-02-13 Impact factor: 6.745

Review 4. Promoting longevity by maintaining metabolic and proliferative homeostasis.

Authors: Lifen Wang; Jason Karpac; Heinrich Jasper
Journal: J Exp Biol Date: 2014-01-01 Impact factor: 3.312

5. Mesenchymal stem cells, aging and regenerative medicine.

Authors: Chiara Raggi; Anna C Berardi
Journal: Muscles Ligaments Tendons J Date: 2012-10-16

6. Identification of small juvenile stem cells in aged bone marrow and their therapeutic potential for repair of the ischemic heart.

Authors: Koichi Igura; Motoi Okada; Ha Won Kim; Muhammad Ashraf
Journal: Am J Physiol Heart Circ Physiol Date: 2013-08-30 Impact factor: 4.733

Review 7. Taste bud homeostasis in health, disease, and aging.

Authors: Pu Feng; Liquan Huang; Hong Wang
Journal: Chem Senses Date: 2013-11-28 Impact factor: 3.160

Review 8. DNA damage and tissue repair: What we can learn from planaria.

Authors: Paul G Barghouth; Manish Thiruvalluvan; Melanie LeGro; Néstor J Oviedo
Journal: Semin Cell Dev Biol Date: 2018-05-03 Impact factor: 7.727

9. Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging.

Authors: Maria M Mihaylova; Chia-Wei Cheng; Amanda Q Cao; Surya Tripathi; Miyeko D Mana; Khristian E Bauer-Rowe; Monther Abu-Remaileh; Laura Clavain; Aysegul Erdemir; Caroline A Lewis; Elizaveta Freinkman; Audrey S Dickey; Albert R La Spada; Yanmei Huang; George W Bell; Vikram Deshpande; Peter Carmeliet; Pekka Katajisto; David M Sabatini; Ömer H Yilmaz
Journal: Cell Stem Cell Date: 2018-05-03 Impact factor: 24.633

Review 10. Cellular mechanisms of somatic stem cell aging.

Authors: Yunjoon Jung; Andrew S Brack
Journal: Curr Top Dev Biol Date: 2014 Impact factor: 4.897