Jeffrey S Ustin1, Mark A Malangoni. 1. Department of Surgery, Division of Trauma, Burns, and Critical Care, Case Western Reserve University, MetroHealth Medical Center Campus, Cleveland, OH, USA.
Abstract
OBJECTIVE: To provide a contemporary review of the diagnosis and management of necrotizing soft-tissue infections. DATA SOURCES: Scientific literature and internet sources. STUDY SELECTION: Major articles of importance in this area. CONCLUSIONS: The mortality for necrotizing soft-tissue infections appears to be decreasing, possibly due to improved recognition and earlier delivery of more effective therapy. Establishing a diagnosis and initiating treatment as soon as possible provides the best opportunity for a good outcome.
OBJECTIVE: To provide a contemporary review of the diagnosis and management of necrotizing soft-tissue infections. DATA SOURCES: Scientific literature and internet sources. STUDY SELECTION: Major articles of importance in this area. CONCLUSIONS: The mortality for necrotizing soft-tissue infections appears to be decreasing, possibly due to improved recognition and earlier delivery of more effective therapy. Establishing a diagnosis and initiating treatment as soon as possible provides the best opportunity for a good outcome.
Authors: Pasquale Niscola; Andrea Tendas; Luca Cupelli; Benedetta Neri; Laura Scaramucci; Luciana Morino; Marco Giovannini; Stefano Fratoni; Paolo de Fabritiis Journal: Support Care Cancer Date: 2012-09-08 Impact factor: 3.603