Literature DB >> 21528622

Providers' beliefs and behaviors regarding antibiotic prescribing and antibiotic resistance in persons with spinal cord injury or disorder.

Charlesnika T Evans1, Thea J Rogers, Frances M Weaver, Stephen P Burns.   

Abstract

CONTEXT: Persons with spinal cord injury or disorder (SCI/D) are at increased risk for antibiotic resistance because of recurrent infections and subsequent use of antibiotics. However, there are no studies focused on providers who care for these patients and their perceptions regarding antibiotic use and resistance.
OBJECTIVE: To characterize SCI/D provider behavior and attitudes about antibiotic prescribing and resistance. DESIGN/
METHODS: Anonymous internet-based, cross-sectional survey. PARTICIPANTS: A total of 314 SCI/D clinicians who prescribe antibiotics (physicians, physician assistants, and nurse practitioners).
RESULTS: A total of 118 providers responded (37.6% response rate) including 80 physicians, 20 nurse practitioners, and 18 physician assistants. The majority of respondents agreed with statements regarding the societal impact of antibiotic resistance; only 17.8% agreed that they prescribed antibiotics more than they should, but 61.0% agreed that patient demand was a major reason for prescribing unnecessary antibiotics. The most frequent problematic organisms reported were: methicillin-resistant Staphylococcus aureus (83.1%), multidrug-resistant Pseudomonas (61.0%), and Clostridium difficile (57.6%). The most frequent antibiotics selected for outpatient treatment of community-acquired pneumonia treatment, based on a clinical scenario were azithromycin (36.4%) and respiratory fluoroquinolones (22.9%).
CONCLUSION: These data show that the respondents are aware of and concerned with the problem of antibiotic resistance in their practice. Clinician respondents also endorsed the need to improve their own knowledge and that of their colleagues regarding appropriate antibiotic prescribing. These findings suggest that interventions should focus on provider education, particularly regarding appropriate antibiotic prescribing.

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Year:  2011        PMID: 21528622      PMCID: PMC3066488          DOI: 10.1179/107902610X12886261091794

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  12 in total

1.  Antibiotic resistance: a survey of physician perceptions.

Authors:  C William Wester; Lakshmi Durairaj; Arthur T Evans; David N Schwartz; Shahid Husain; Enrique Martinez
Journal:  Arch Intern Med       Date:  2002-10-28

2.  Clinicians' perceptions of the problem of antimicrobial resistance in health care facilities.

Authors:  Tara Bridget Giblin; Ronda L Sinkowitz-Cochran; Patricia L Harris; Sharon Jacobs; Kathy Liberatore; Marsha A Palfreyman; Edward I Harrison; Denise M Cardo
Journal:  Arch Intern Med       Date:  2004 Aug 9-23

3.  Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship.

Authors:  Timothy H Dellit; Robert C Owens; John E McGowan; Dale N Gerding; Robert A Weinstein; John P Burke; W Charles Huskins; David L Paterson; Neil O Fishman; Christopher F Carpenter; P J Brennan; Marianne Billeter; Thomas M Hooton
Journal:  Clin Infect Dis       Date:  2006-12-13       Impact factor: 9.079

4.  An epidemic, toxin gene-variant strain of Clostridium difficile.

Authors:  L Clifford McDonald; George E Killgore; Angela Thompson; Robert C Owens; Sophia V Kazakova; Susan P Sambol; Stuart Johnson; Dale N Gerding
Journal:  N Engl J Med       Date:  2005-12-01       Impact factor: 91.245

Review 5.  Infections in patients with spinal cord injuries.

Authors:  J Z Montgomerie
Journal:  Clin Infect Dis       Date:  1997-12       Impact factor: 9.079

6.  Tensions in antibiotic prescribing: pitting social concerns against the interests of individual patients.

Authors:  Joshua P Metlay; Judy A Shea; Linda B Crossette; David A Asch
Journal:  J Gen Intern Med       Date:  2002-02       Impact factor: 5.128

7.  Antibiotic treatment of adults with sore throat by community primary care physicians: a national survey, 1989-1999.

Authors:  J A Linder; R S Stafford
Journal:  JAMA       Date:  2001-09-12       Impact factor: 56.272

8.  Changing use of antibiotics in community-based outpatient practice, 1991-1999.

Authors:  Michael A Steinman; Ralph Gonzales; Jeffrey A Linder; C Seth Landefeld
Journal:  Ann Intern Med       Date:  2003-04-01       Impact factor: 25.391

9.  Epidemiology of hospital-acquired infections in veterans with spinal cord injury and disorder.

Authors:  Charlesnika T Evans; Sherri L LaVela; Frances M Weaver; Michael Priebe; Paul Sandford; Pamela Niemiec; Scott Miskevics; Jorge P Parada
Journal:  Infect Control Hosp Epidemiol       Date:  2008-03       Impact factor: 3.254

10.  Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults.

Authors:  Lionel A Mandell; John G Bartlett; Scott F Dowell; Thomas M File; Daniel M Musher; Cynthia Whitney
Journal:  Clin Infect Dis       Date:  2003-11-03       Impact factor: 9.079

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  11 in total

1.  Primary Care Physicians' Attitudes and Perceptions Towards Antibiotic Resistance and Antibiotic Stewardship: A National Survey.

Authors:  Rachel M Zetts; Andrea M Garcia; Jason N Doctor; Jeffrey S Gerber; Jeffrey A Linder; David Y Hyun
Journal:  Open Forum Infect Dis       Date:  2020-06-20       Impact factor: 3.835

2.  Clinicians' knowledge, attitudes, and practices regarding infections with multidrug-resistant gram-negative bacilli in intensive care units.

Authors:  Juyan Julia Zhou; Sameer J Patel; Haomiao Jia; Scott A Weisenberg; E Yoko Furuya; Christine J Kubin; Luis Alba; Kyu Rhee; Lisa Saiman
Journal:  Infect Control Hosp Epidemiol       Date:  2013-01-24       Impact factor: 3.254

Review 3.  Gut Microbiota Are Disease-Modifying Factors After Traumatic Spinal Cord Injury.

Authors:  Kristina A Kigerl; Klauss Mostacada; Phillip G Popovich
Journal:  Neurotherapeutics       Date:  2018-01       Impact factor: 7.620

4.  Antibiotic prescribing trends in the emergency department for veterans with spinal cord injury and disorder 2002-2007.

Authors:  Charlesnika T Evans; Thea J Rogers; Amy Chin; Stuart Johnson; Bridget Smith; Frances M Weaver; Stephen P Burns
Journal:  J Spinal Cord Med       Date:  2013-09       Impact factor: 1.985

5.  Gut dysbiosis impairs recovery after spinal cord injury.

Authors:  Kristina A Kigerl; Jodie C E Hall; Lingling Wang; Xiaokui Mo; Zhongtang Yu; Phillip G Popovich
Journal:  J Exp Med       Date:  2016-10-17       Impact factor: 14.307

6.  Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment.

Authors:  John C Gensel; Timothy J Kopper; Bei Zhang; Michael B Orr; William M Bailey
Journal:  Sci Rep       Date:  2017-01-06       Impact factor: 4.379

7.  Primary care physicians' attitudes and perceptions towards antibiotic resistance and outpatient antibiotic stewardship in the USA: a qualitative study.

Authors:  Rachel M Zetts; Andrea Stoesz; Andrea M Garcia; Jason N Doctor; Jeffrey S Gerber; Jeffrey A Linder; David Y Hyun
Journal:  BMJ Open       Date:  2020-07-14       Impact factor: 2.692

8.  Macrolide derivatives reduce proinflammatory macrophage activation and macrophage-mediated neurotoxicity.

Authors:  Bei Zhang; Timothy J Kopper; Xiaodong Liu; Zheng Cui; Steven G Van Lanen; John C Gensel
Journal:  CNS Neurosci Ther       Date:  2019-01-24       Impact factor: 5.243

9.  Sexual Dimorphism of Pain Control: Analgesic Effects of Pioglitazone and Azithromycin in Chronic Spinal Cord Injury.

Authors:  John C Gensel; Renée R Donahue; William M Bailey; Bradley K Taylor
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10.  Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury.

Authors:  Bei Zhang; William M Bailey; Timothy J Kopper; Michael B Orr; David J Feola; John C Gensel
Journal:  J Neuroinflammation       Date:  2015-11-24       Impact factor: 8.322

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