Literature DB >> 21524573

New antiplasmodial indole alkaloids from Hunteria zeylanica.

Alfarius E Nugroho1, Masatomo Sugai, Yusuke Hirasawa, Takahiro Hosoya, Khalijah Awang, A Hamid A Hadi, Wiwied Ekasari, Aty Widyawaruyanti, Hiroshi Morita.   

Abstract

Two new indole alkaloids, bisnicalaterine D (1), consisting of an eburnane and a corynanthe type of skeletons, and nicalaterine A (2) were isolated from the bark of Hunteria zeylanica. Their structures were elucidated by various spectroscopic data such as NMR and CD spectra. A series of bisnicalaterines and nicalaterine A showed potent antiplasmodial activity against Plasmodium falciparum 3D7.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21524573     DOI: 10.1016/j.bmcl.2011.03.104

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia.

Authors:  Yiming Tang; Alfarius Eko Nugroho; Yusuke Hirasawa; Takahiro Tougan; Toshihiro Horii; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2019-03-25       Impact factor: 2.343

2.  Antimalarial Natural Products.

Authors:  David G I Kingston; Maria Belen Cassera
Journal:  Prog Chem Org Nat Prod       Date:  2022
  2 in total

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