| Literature DB >> 21518835 |
C C Papagiannitsis1, S D Kotsakis, E Petinaki, A C Vatopoulos, E Tzelepi, V Miriagou, L S Tzouvelekis.
Abstract
VIM-27 metallo-β-lactamase, an Ala(57) → Ser variant of VIM-1, was identified in three Klebsiella pneumoniae isolates belonging to sequence type 147. bla(VIM-27) was part of a class 1 integron carried by non-self-transferable plasmids. Kinetic parameters and MIC determinations indicated that VIM-27 hydrolyzed most β-lactams, especially imipenem and cefoxitin, less effectively than VIM-1.Entities:
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Year: 2011 PMID: 21518835 PMCID: PMC3122466 DOI: 10.1128/AAC.00238-11
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191