Muriel M Schornack1. 1. Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA. Schornack.muriel@mayo.edu
Abstract
BACKGROUND: Limbal stem cell deficiency (LSCD) results from damage to or destruction of corneal stem cells. METHODS: A retrospective review of clinical records of a patient with LSCD describes the use of scleral lenses in disease management. RESULTS: A patient presented with a one-year history of clinically diagnosed LSCD, which was worsening despite aggressive topical and systemic medical therapy. The condition resolved rapidly with initiation of scleral lens wear. The integrity of the ocular surface was maintained for 18 months even after the cessation of lens wear. CONCLUSION: Scleral lenses might allow some patients with LSCD to delay or avoid more aggressive surgical intervention.
BACKGROUND: Limbal stem cell deficiency (LSCD) results from damage to or destruction of corneal stem cells. METHODS: A retrospective review of clinical records of a patient with LSCD describes the use of scleral lenses in disease management. RESULTS: A patient presented with a one-year history of clinically diagnosed LSCD, which was worsening despite aggressive topical and systemic medical therapy. The condition resolved rapidly with initiation of scleral lens wear. The integrity of the ocular surface was maintained for 18 months even after the cessation of lens wear. CONCLUSION: Scleral lenses might allow some patients with LSCD to delay or avoid more aggressive surgical intervention.
Authors: Michel Haagdorens; Sara Ilse Van Acker; Veerle Van Gerwen; Sorcha Ní Dhubhghaill; Carina Koppen; Marie-José Tassignon; Nadia Zakaria Journal: Stem Cells Int Date: 2015-12-14 Impact factor: 5.443
Authors: Sohil Amin; Elmira Jalilian; Eitan Katz; Charlie Frank; Ghasem Yazdanpanah; Victor H Guaiquil; Mark I Rosenblatt; Ali R Djalilian Journal: Vision (Basel) Date: 2021-09-22