| Literature DB >> 27480488 |
Jennifer Rossen1, Alec Amram1, Behrad Milani1, Dongwook Park1, Jennifer Harthan2, Charlotte Joslin1, Timothy McMahon1, Ali Djalilian3.
Abstract
Limbal stem cell deficiency (LSCD) is a pathologic condition caused by the dysfunction and/or destruction of stem cell precursors of the corneal epithelium, typified clinically by corneal conjunctivalization. The purpose of this review is to critically discuss a less well-known cause of limbal stem cell disease: contact lens (CL) wear. A literature search was conducted to include original articles containing patients with CL-induced LSCD. This review describes epidemiology, diagnostic strategies, pathogenesis, differential diagnosis, and treatment modalities for this condition.Entities:
Keywords: contact lens; corneal conjunctivalization; limbal stem cell deficiency; limbal stem cells
Mesh:
Year: 2016 PMID: 27480488 PMCID: PMC5065783 DOI: 10.1016/j.jtos.2016.06.003
Source DB: PubMed Journal: Ocul Surf ISSN: 1542-0124 Impact factor: 5.033