Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Characterization of a high-spin non-heme Fe(III)-OOH intermediate and its quantitative conversion to an Fe(IV)═O complex.

Literature DB >> 21517091

Characterization of a high-spin non-heme Fe(III)-OOH intermediate and its quantitative conversion to an Fe(IV)═O complex.

Feifei Li¹, Katlyn K Meier, Matthew A Cranswick, Mrinmoy Chakrabarti, Katherine M Van Heuvelen, Eckard Münck, Lawrence Que.

Abstract

We have generated a high-spin Fe(III)-OOH complex supported by tetramethylcyclam via protonation of its conjugate base and characterized it in detail using various spectroscopic methods. This Fe(III)-OOH species can be converted quantitatively to an Fe(IV)═O complex via O-O bond cleavage; this is the first example of such a conversion. This conversion is promoted by two factors: the strong Fe(III)-OOH bond, which inhibits Fe-O bond lysis, and the addition of protons, which facilitates O-O bond cleavage. This example provides a synthetic precedent for how O-O bond cleavage of high-spin Fe(III)-peroxo intermediates of non-heme iron enzymes may be promoted.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2011 PMID： 21517091 PMCID： PMC3097042 DOI： 10.1021/ja111742z

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

36 in total

Review 1. Finding intermediates in the O2 activation pathways of non-heme iron oxygenases.

Authors: E G Kovaleva; M B Neibergall; S Chakrabarty; J D Lipscomb
Journal: Acc Chem Res Date: 2007-06-14 Impact factor: 22.384

2. Olefin cis-dihydroxylation versus epoxidation by non-heme iron catalysts: two faces of an Fe(III)-OOH coin.

Authors: Kui Chen; Miquel Costas; Jinheung Kim; Adrianne K Tipton; Lawrence Que
Journal: J Am Chem Soc Date: 2002-03-27 Impact factor: 15.419

3. Thirty years of microbial P450 monooxygenase research: peroxo-heme intermediates--the central bus station in heme oxygenase catalysis.

Authors: Stephen G Sligar; Thomas M Makris; Ilia G Denisov
Journal: Biochem Biophys Res Commun Date: 2005-08-24 Impact factor: 3.575

4. Chemical and spectroscopic evidence for an FeV-oxo complex.

Authors: Filipe Tiago de Oliveira; Arani Chanda; Deboshri Banerjee; Xiaopeng Shan; Sujit Mondal; Lawrence Que; Emile L Bominaar; Eckard Münck; Terrence J Collins
Journal: Science Date: 2006-12-21 Impact factor: 47.728

5. Synthetic models for the cysteinate-ligated non-heme iron enzyme superoxide reductase: observation and structural characterization by XAS of an Fe(III)-OOH intermediate.

Authors: Jason Shearer; Robert C Scarrow; Julie A Kovacs
Journal: J Am Chem Soc Date: 2002-10-02 Impact factor: 15.419

6. Active site threonine facilitates proton transfer during dioxygen activation at the diiron center of toluene/o-xylene monooxygenase hydroxylase.

Authors: Woon Ju Song; Michael S McCormick; Rachel K Behan; Matthew H Sazinsky; Wei Jiang; Jeffery Lin; Carsten Krebs; Stephen J Lippard
Journal: J Am Chem Soc Date: 2010-10-06 Impact factor: 15.419

7. Near-stoichiometric conversion of H(2)O(2) to Fe(IV)=O at a nonheme iron(II) center. Insights into the O-O bond cleavage step.

Authors: Feifei Li; Jason England; Lawrence Que
Journal: J Am Chem Soc Date: 2010-02-24 Impact factor: 15.419

8. Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): evidence for a multi-step, proton-dependent reaction pathway.

Authors: Christine E Tinberg; Stephen J Lippard
Journal: Biochemistry Date: 2009-12-29 Impact factor: 3.162

9. Reactivities of oxo and peroxo intermediates studied by hemoprotein mutants.

Authors: Yoshihito Watanabe; Hiroshi Nakajima; Takafumi Ueno
Journal: Acc Chem Res Date: 2007-06-14 Impact factor: 22.384

10. Dioxygen activation by mononuclear nonheme iron(II) complexes generates iron-oxygen intermediates in the presence of an NADH analogue and proton.

Authors: Seungwoo Hong; Yong-Min Lee; Woonsup Shin; Shunichi Fukuzumi; Wonwoo Nam
Journal: J Am Chem Soc Date: 2009-10-07 Impact factor: 15.419

24 in total

1. Sc3+-triggered oxoiron(IV) formation from O2 and its non-heme iron(II) precursor via a Sc3+-peroxo-Fe3+ intermediate.

Authors: Feifei Li; Katherine M Van Heuvelen; Katlyn K Meier; Eckard Münck; Lawrence Que
Journal: J Am Chem Soc Date: 2013-07-02 Impact factor: 15.419

2. An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway.

Authors: Thomas M Makris; Van V Vu; Katlyn K Meier; Anna J Komor; Brent S Rivard; Eckard Münck; Lawrence Que; John D Lipscomb
Journal: J Am Chem Soc Date: 2015-01-21 Impact factor: 15.419

3. Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 from Mycobacterium tuberculosis proceeds through a catalytic shunt pathway.

Authors: Kednerlin Dornevil; Ian Davis; Andrew J Fielding; James R Terrell; Li Ma; Aimin Liu
Journal: J Biol Chem Date: 2017-06-30 Impact factor: 5.157

Review 4. Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.

Authors: Subhasree Kal; Lawrence Que
Journal: J Biol Inorg Chem Date: 2017-01-10 Impact factor: 3.358

5. Sc³⁺-Promoted O-O Bond Cleavage of a (μ-1,2-Peroxo)diiron(III) Species Formed from an Iron(II) Precursor and O₂ to Generate a Complex with an Fe^IV₂(μ-O)₂ Core.

Authors: Saikat Banerjee; Apparao Draksharapu; Patrick M Crossland; Ruixi Fan; Yisong Guo; Marcel Swart; Lawrence Que
Journal: J Am Chem Soc Date: 2020-02-19 Impact factor: 15.419