Validation of optical low coherence reflectometry retinal and choroidal biometry.

PURPOSE: To compare measurements of retinal thickness (RT) and choroidal thickness (ChT) obtained with an optical low coherence reflectometry (OLCR) biometer (Lenstar LS 900) with those obtained with a spectral domain optical coherence tomographer (SD OCT) (Copernicus SOCT HR) in young normal subjects.
METHODS: Twenty young adult subjects had foveal RT and subfoveal ChT measurements obtained with OLCR biometry and SD OCT. RT and ChT was derived through manual analysis of A-scan data from the OLCR biometer. An average SD OCT foveal B-scan image derived from a series of 50 multiple B-scans was also analyzed to determine RT and ChT for each subject. Measurements from the two instruments were compared using Pearson correlation and Bland-Altman analysis.
RESULTS: RT and ChT measurements from the two instruments were highly correlated (r of 0.80 and 0.94, respectively, p<0.0001). The mean RT with SD OCT and OLCR were 195 ± 17 μm and 196 ± 16 μm, respectively (mean difference, 1 ± 8 μm). The mean ChT was 324 ± 71 μm and 328 ± 84 μm with SD OCT and OLCR, respectively (mean difference, 4 ± 24 μm).
CONCLUSIONS: Foveal RT and subfoveal ChT measures from OLCR biometry exhibit a strong correlation and good agreement with measures derived from SD OCT in a population of young adult subjects.