OBJECTIVE: The objective of the study was to provide information on overall medication use throughout pregnancy, with particular focus on the first trimester and specific prescription medications. STUDY DESIGN: The study design included the Slone Epidemiology Center Birth Defects Study, 1976-2008, and the National Birth Defects Prevention Study, 1997-2003, which together interviewed more than 30,000 women about their antenatal medication use. RESULTS: Over the last 3 decades, first-trimester use of prescription medication increased by more than 60%, and the use of 4 or more medications more than tripled. By 2008, approximately 50% of women reported taking at least 1 medication. Use of some specific medications markedly decreased or increased. Prescription medication use increased with maternal age and education, was highest for non-Hispanic whites, and varied by state. CONCLUSION: These data reflect the widespread and growing use of medications by pregnant women and reinforce the need to study their respective fetal risks and safety.
OBJECTIVE: The objective of the study was to provide information on overall medication use throughout pregnancy, with particular focus on the first trimester and specific prescription medications. STUDY DESIGN: The study design included the Slone Epidemiology Center Birth Defects Study, 1976-2008, and the National Birth Defects Prevention Study, 1997-2003, which together interviewed more than 30,000 women about their antenatal medication use. RESULTS: Over the last 3 decades, first-trimester use of prescription medication increased by more than 60%, and the use of 4 or more medications more than tripled. By 2008, approximately 50% of women reported taking at least 1 medication. Use of some specific medications markedly decreased or increased. Prescription medication use increased with maternal age and education, was highest for non-Hispanic whites, and varied by state. CONCLUSION: These data reflect the widespread and growing use of medications by pregnant women and reinforce the need to study their respective fetal risks and safety.
Authors: Susan E Andrade; Jerry H Gurwitz; Robert L Davis; K Arnold Chan; Jonathan A Finkelstein; Kris Fortman; Heather McPhillips; Marsha A Raebel; Douglas Roblin; David H Smith; Marianne Ulcickas Yood; Abraham N Morse; Richard Platt Journal: Am J Obstet Gynecol Date: 2004-08 Impact factor: 8.661
Authors: Mary Jane Welch; Rachel Lally; Jennifer E Miller; Stephanie Pittman; Lynda Brodsky; Arthur L Caplan; Gina Uhlenbrauck; Darcy M Louzao; James H Fischer; Benjamin Wilfond Journal: Clin Trials Date: 2015-09-15 Impact factor: 2.486
Authors: Lily Lie; Vishwas Shetty; Karan Gupta; Janine E Polifka; Glen Markham; Sarah Albee; Carol Collins; Gary Hsieh Journal: AMIA Annu Symp Proc Date: 2018-04-16
Authors: J Wang; T Johnson; L Sahin; M S Tassinari; P O Anderson; T E Baker; C Bucci-Rechtweg; G J Burckart; C D Chambers; T W Hale; D Johnson-Lyles; R M Nelson; C Nguyen; D Pica-Branco; Z Ren; H Sachs; J Sauberan; A Zajicek; S Ito; L P Yao Journal: Clin Pharmacol Ther Date: 2017-06 Impact factor: 6.875
Authors: Brian T Bateman; Sonia Hernandez-Diaz; James P Rathmell; John D Seeger; Michael Doherty; Michael A Fischer; Krista F Huybrechts Journal: Anesthesiology Date: 2014-05 Impact factor: 7.892
Authors: Molly M Lynch; Linda B Squiers; Katherine M Kosa; Suzanne Dolina; Jennifer Gard Read; Cheryl S Broussard; Meghan T Frey; Kara N Polen; Jennifer N Lind; Suzanne M Gilboa; Janis Biermann Journal: Matern Child Health J Date: 2018-01