Literature DB >> 21514215

Kojic acid biosynthesis in Aspergillus oryzae is regulated by a Zn(II)(2)Cys(6) transcriptional activator and induced by kojic acid at the transcriptional level.

Junichiro Marui1, Noriko Yamane, Sumiko Ohashi-Kunihiro, Tomohiro Ando, Yasunobu Terabayashi, Motoaki Sano, Shinichi Ohashi, Eiji Ohshima, Kuniharu Tachibana, Yoshitaka Higa, Marie Nishimura, Hideaki Koike, Masayuki Machida.   

Abstract

A gene encoding the Zn(II)(2)Cys(6) transcriptional factor is clustered with two genes involved in biosynthesis of a secondary metabolite, kojic acid (KA), in Aspergillus oryzae. We determined that the gene was essential for KA production and the transcriptional activation of KA biosynthetic genes, which were triggered by the addition of KA.
Copyright © 2011 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 21514215     DOI: 10.1016/j.jbiosc.2011.03.010

Source DB:  PubMed          Journal:  J Biosci Bioeng        ISSN: 1347-4421            Impact factor:   2.894


  29 in total

Review 1.  Advances in Aspergillus secondary metabolite research in the post-genomic era.

Authors:  James F Sanchez; Amber D Somoza; Nancy P Keller; Clay C C Wang
Journal:  Nat Prod Rep       Date:  2012-01-06       Impact factor: 13.423

2.  Construction of single, double, or triple mutants within kojic acid synthesis genes kojA, kojR, and kojT by the CRISPR/Cas9 tool in Aspergillus oryzae.

Authors:  Yuzhen Li; Huanxin Zhang; Ziming Chen; Junxia Fan; Tianming Chen; Bin Zeng; Zhe Zhang
Journal:  Folia Microbiol (Praha)       Date:  2022-01-15       Impact factor: 2.099

3.  Overexpression of a novel gene Aokap2 affects the growth and kojic acid production in Aspergillus oryzae.

Authors:  Yuzhen Li; Huanxin Zhang; Ziming Chen; Junxia Fan; Tianming Chen; Yi Xiao; Junyin Jie; Bin Zeng; Zhe Zhang
Journal:  Mol Biol Rep       Date:  2022-01-16       Impact factor: 2.316

4.  Disruption of Aokap6 near the kojic acid gene cluster affects the growth and kojic acid production in Aspergillus oryzae.

Authors:  Ziming Chen; Tianming Chen; Huilan Wang; Conghua Jiang; Yixue Liu; Xinyu Wu; Yuzhen Li; Bin Zeng; Zhe Zhang
Journal:  World J Microbiol Biotechnol       Date:  2022-08-04       Impact factor: 4.253

5.  SfgA Renders Aspergillus flavus More Stable to the External Environment.

Authors:  Xiao-Yu Yuan; Jie-Ying Li; Qing-Qing Zhi; Sheng-Da Chi; Su Qu; Yan-Feng Luo; Zhu-Mei He
Journal:  J Fungi (Basel)       Date:  2022-06-16

6.  Identification and characterization of the ZRT, IRT-like protein (ZIP) family genes reveal their involvement in growth and kojic acid production in Aspergillus oryzae.

Authors:  Zhe Zhang; Junxia Fan; Chuannan Long; Bin He; Zhihong Hu; Chunmiao Jiang; Yongkai Li; Long Ma; Jingshang Wen; Xiaojin Zou; Yuan Chen; Zhenxiang Ge; Bin Zeng
Journal:  J Ind Microbiol Biotechnol       Date:  2019-09-20       Impact factor: 3.346

7.  Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus.

Authors:  Ry R Forseth; Saori Amaike; Daniel Schwenk; Katharyn J Affeldt; Dirk Hoffmeister; Frank C Schroeder; Nancy P Keller
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-20       Impact factor: 15.336

8.  Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins.

Authors:  J C Frisvad; V Hubka; C N Ezekiel; S-B Hong; A Nováková; A J Chen; M Arzanlou; T O Larsen; F Sklenář; W Mahakarnchanakul; R A Samson; J Houbraken
Journal:  Stud Mycol       Date:  2018-07-31       Impact factor: 16.097

9.  Identification and characterization of a novel gene Aokap1 involved in growth and kojic acid synthesis in Aspergillus oryzae.

Authors:  Yuzhen Li; Huanxin Zhang; Ziming Chen; Junxia Fan; Tianming Chen; Bin Zeng; Zhe Zhang
Journal:  Arch Microbiol       Date:  2021-12-23       Impact factor: 2.552

10.  Comparative genome analysis between Aspergillus oryzae strains reveals close relationship between sites of mutation localization and regions of highly divergent genes among Aspergillus species.

Authors:  Myco Umemura; Hideaki Koike; Noriko Yamane; Yoshinori Koyama; Yuki Satou; Ikuya Kikuzato; Morimi Teruya; Masatoshi Tsukahara; Yumi Imada; Youji Wachi; Yukino Miwa; Shuichi Yano; Koichi Tamano; Yutaka Kawarabayasi; Kazuhiro E Fujimori; Masayuki Machida; Takashi Hirano
Journal:  DNA Res       Date:  2012-08-21       Impact factor: 4.458

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