Literature DB >> 21513295

Nocardioazines: a novel bridged diketopiperazine scaffold from a marine-derived bacterium inhibits P-glycoprotein.

Ritesh Raju1, Andrew M Piggott, Xiao-Cong Huang, Robert J Capon.   

Abstract

An Australian marine sediment-derived isolate, Nocardiopsis sp. (CMB-M0232), yielded a new class of prenylated diketopiperazine, indicative of the action of a uniquely regioselective diketopiperazine indole prenyltransferase. The bridged scaffold of nocardioazine A proved to be a noncytotoxic inhibitor of the membrane protein efflux pump P-glycoprotein, reversing doxorubicin resistance in a multidrug resistant colon cancer cell.

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Year:  2011        PMID： 21513295     DOI： 10.1021/ol200904v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  16 in total

Review 1.  Genus Nocardiopsis: A Prolific Producer of Natural Products.

Authors:  Ting Shi; Yi-Fei Wang; Han Wang; Bo Wang
Journal:  Mar Drugs       Date:  2022-05-31       Impact factor: 6.085

2.  Enantioselective total synthesis of (-)-lansai B and (+)-nocardioazines A and B.

Authors:  Haoxuan Wang; Sarah E Reisman
Journal:  Angew Chem Int Ed Engl       Date:  2014-04-28       Impact factor: 15.336

3.  Bioinspired Brønsted Acid-Promoted Regioselective Tryptophan Isoprenylations.

Authors:  Tushar M Khopade; Kalyani Ajayan; Swapnil S Joshi; Amy L Lane; Rajesh Viswanathan
Journal:  ACS Omega       Date:  2021-04-12

Review 4.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

Review 5.  Marine natural products with P-glycoprotein inhibitor properties.

Authors:  Dioxelis Lopez; Sergio Martinez-Luis
Journal:  Mar Drugs       Date:  2014-01-22       Impact factor: 5.118

Review 6.  An update on 2,5-diketopiperazines from marine organisms.

Authors:  Ri-Ming Huang; Xiang-Xi Yi; Yuying Zhou; Xiangdong Su; Yan Peng; Cheng-Hai Gao
Journal:  Mar Drugs       Date:  2014-12-19       Impact factor: 5.118

7.  Three diketomorpholines from a Penicillium sp. (strain G1071).

Authors:  Zeinab Y Al Subeh; Huzefa A Raja; Joanna E Burdette; Joseph O Falkinham; Scott E Hemby; Nicholas H Oberlies
Journal:  Phytochemistry       Date:  2021-06-20       Impact factor: 4.004

Review 8.  Marine Indole Alkaloids.

Authors:  Natalie Netz; Till Opatz
Journal:  Mar Drugs       Date:  2015-08-06       Impact factor: 5.118

9.  Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells.

Authors:  Xiao-Cong Huang; Xue Xiao; Yun-Kai Zhang; Tanaji T Talele; Angela A Salim; Zhe-Sheng Chen; Robert J Capon
Journal:  Mar Drugs       Date:  2014-06-27       Impact factor: 5.118

Review 10.  Natural Product Potential of the Genus Nocardiopsis.

Authors:  Alyaa Hatem Ibrahim; Samar Yehia Desoukey; Mostafa A Fouad; Mohamed Salah Kamel; Tobias A M Gulder; Usama Ramadan Abdelmohsen
Journal:  Mar Drugs       Date:  2018-04-29       Impact factor: 5.118
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