Literature DB >> 21512525

Induced pluripotent stem cells: an emerging theranostics platform.

T J Nelson1, A Terzic.   

Abstract

Nuclear reprogramming generates induced pluripotent stem (iPS) cells endowed with the unlimited potential to reconstruct genetically identical tissues. This biomedical tool offers unprecedented opportunities to develop scalable yet personalized cell-based reagents. The emerging platform of regenerative theranostics provides a unique approach to expose mechanisms of disease etiology in the context of dysfunctional cell biology. Resolved molecular dynamics that define and regulate the regenerative capacity of individual stem cells will enable next-generation, patient-specific diagnostic and therapeutic applications.

Entities:  

Mesh：

Year:  2011        PMID： 21512525     DOI： 10.1038/clpt.2010.304

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  21 in total

1.  Metabolome and metaboproteome remodeling in nuclear reprogramming.

Authors:  Clifford Dl Folmes; D Kent Arrell; Jelena Zlatkovic-Lindor; Almudena Martinez-Fernandez; Carmen Perez-Terzic; Timothy J Nelson; Andre Terzic
Journal:  Cell Cycle       Date:  2013-07-08       Impact factor: 4.534

2.  Regenerative medicine: on the vanguard of health care.

Authors:  Andre Terzic; Clifford D Folmes; Almudena Martinez-Fernandez; Atta Behfar
Journal:  Mayo Clin Proc       Date:  2011-07       Impact factor: 7.616

Review 3.  Stem Cell Spheroids and Ex Vivo Niche Modeling: Rationalization and Scaling-Up.

Authors:  Isotta Chimenti; Diana Massai; Umberto Morbiducci; Antonio Paolo Beltrami; Maurizio Pesce; Elisa Messina
Journal:  J Cardiovasc Transl Res       Date:  2017-03-13       Impact factor: 4.132

4.  Impedance of novel therapeutic technologies: the case of stem cells.

Authors:  David G Zacharias; Timothy J Nelson; Paul S Mueller; C Christopher Hook
Journal:  Clin Transl Sci       Date:  2012-06-28       Impact factor: 4.689

5.  The value proposition of molecular medicine.

Authors:  Scott A Waldman; Andre Terzic
Journal:  Clin Transl Sci       Date:  2012-02-23       Impact factor: 4.689

Review 6.  Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery.

Authors:  Katherine A Campbell; Andre Terzic; Timothy J Nelson
Journal:  Regen Med       Date:  2015-10-06       Impact factor: 3.806

Review 7.  Energy metabolism in nuclear reprogramming.

Authors:  Clifford D L Folmes; Timothy J Nelson; Andre Terzic
Journal:  Biomark Med       Date:  2011-12       Impact factor: 2.851

Review 8.  Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association.

Authors:  Kiran Musunuru; Farah Sheikh; Rajat M Gupta; Steven R Houser; Kevin O Maher; David J Milan; Andre Terzic; Joseph C Wu
Journal:  Circ Genom Precis Med       Date:  2018-01-12

9.  Transcriptional atlas of cardiogenesis maps congenital heart disease interactome.

Authors:  Xing Li; Almudena Martinez-Fernandez; Katherine A Hartjes; Jean-Pierre A Kocher; Timothy M Olson; Andre Terzic; Timothy J Nelson
Journal:  Physiol Genomics       Date:  2014-05-06       Impact factor: 3.107

10.  Nuclear reprogramming with c-Myc potentiates glycolytic capacity of derived induced pluripotent stem cells.

Authors:  Clifford D L Folmes; Almudena Martinez-Fernandez; Randolph S Faustino; Satsuki Yamada; Carmen Perez-Terzic; Timothy J Nelson; Andre Terzic
Journal:  J Cardiovasc Transl Res       Date:  2012-12-18       Impact factor: 4.132
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