Literature DB >> 21509930

Time-to-antibiotic administration as a quality of care measure in children with febrile neutropenia: a survey of pediatric oncology centers.

Timothy L McCavit1, Naomi Winick.   

Abstract

Time-to-antibiotic administration (TTA) has been suggested as a quality-of-care (QOC) measure for pediatric oncology patients with febrile neutropenia (FN). Unknown, however, is to what extent pediatric oncology centers utilize TTA. Therefore, we designed and administered an electronic survey (68% response rate) of programs in the Children's Oncology Group to assess TTA utilization. Nearly half of respondents track TTA. Most reported using a benchmark of less than 60 min from arrival. TTA is a commonly used QOC measure for pediatric FN despite an absence of studies establishing its validity and a lack of data supporting its impact on outcomes of FN.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 21509930      PMCID: PMC3150359          DOI: 10.1002/pbc.23148

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN: 1545-5009            Impact factor:   3.167


  12 in total

1.  Identification of 90% of patients ultimately diagnosed with community-acquired pneumonia within four hours of emergency department arrival may not be feasible.

Authors:  Christopher Fee; Ellen J Weber
Journal:  Ann Emerg Med       Date:  2007-01-08       Impact factor: 5.721

2.  Detrimental role of delayed antibiotic administration and penicillin-nonsusceptible strains in adult intensive care unit patients with pneumococcal meningitis: the PNEUMOREA prospective multicenter study.

Authors:  Marc Auburtin; Michel Wolff; Julien Charpentier; Emmanuelle Varon; Yves Le Tulzo; Christophe Girault; Ismaël Mohammedi; Benoît Renard; Bruno Mourvillier; Fabrice Bruneel; Jean-Damien Ricard; Jean-François Timsit
Journal:  Crit Care Med       Date:  2006-11       Impact factor: 7.598

3.  Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.

Authors:  Anand Kumar; Daniel Roberts; Kenneth E Wood; Bruce Light; Joseph E Parrillo; Satendra Sharma; Robert Suppes; Daniel Feinstein; Sergio Zanotti; Leo Taiberg; David Gurka; Aseem Kumar; Mary Cheang
Journal:  Crit Care Med       Date:  2006-06       Impact factor: 7.598

4.  Community-acquired bacterial meningitis in adults: antibiotic timing in disease course and outcome.

Authors:  D Lepur; B Barsić
Journal:  Infection       Date:  2007-07-23       Impact factor: 3.553

5.  Delay of adequate empiric antibiotic therapy is associated with increased mortality among solid-organ transplant patients.

Authors:  B Hamandi; A M Holbrook; A Humar; J Brunton; E A Papadimitropoulos; G G Wong; L Thabane
Journal:  Am J Transplant       Date:  2009-05-20       Impact factor: 8.086

Review 6.  The quality of care. How can it be assessed?

Authors:  A Donabedian
Journal:  JAMA       Date:  1988 Sep 23-30       Impact factor: 56.272

7.  Quality of care, process, and outcomes in elderly patients with pneumonia.

Authors:  T P Meehan; M J Fine; H M Krumholz; J D Scinto; D H Galusha; J T Mockalis; G F Weber; M K Petrillo; P M Houck; J M Fine
Journal:  JAMA       Date:  1997-12-17       Impact factor: 56.272

8.  Delay of active antimicrobial therapy and mortality among patients with bacteremia: impact of severe neutropenia.

Authors:  Michael Y Lin; Robert A Weinstein; Bala Hota
Journal:  Antimicrob Agents Chemother       Date:  2008-07-14       Impact factor: 5.191

9.  Antibiotics in 30 minutes or less for febrile neutropenic patients: a quality control measure in a new hospital.

Authors:  Amy L Corey; Stacy Snyder
Journal:  J Pediatr Oncol Nurs       Date:  2008-06-06       Impact factor: 1.636

10.  Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia.

Authors:  Peter M Houck; Dale W Bratzler; Wato Nsa; Allen Ma; John G Bartlett
Journal:  Arch Intern Med       Date:  2004-03-22
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  11 in total

1.  Cohort study of the impact of time to antibiotic administration on mortality in patients with febrile neutropenia.

Authors:  Regis G Rosa; Luciano Z Goldani
Journal:  Antimicrob Agents Chemother       Date:  2014-04-21       Impact factor: 5.191

2.  Association of time to antibiotics and clinical outcomes in patients with fever and neutropenia during chemotherapy for cancer: a systematic review.

Authors:  Christa Koenig; Christine Schneider; Jessica E Morgan; Roland A Ammann; Lillian Sung; Bob Phillips
Journal:  Support Care Cancer       Date:  2019-07-01       Impact factor: 3.603

3.  Protocol for Reducing Time to Antibiotics in Pediatric Patients Presenting to an Emergency Department With Fever and Neutropenia: Efficacy and Barriers.

Authors:  Clay Cohen; Amber King; Chee Paul Lin; Gregory K Friedman; Kathy Monroe; Matthew Kutny
Journal:  Pediatr Emerg Care       Date:  2016-11       Impact factor: 1.454

4.  The Golden Hour: Sustainability and Clinical Outcomes of Adequate Time to Antibiotic Administration in Children with Cancer and Febrile Neutropenia in Northwestern Mexico.

Authors:  Miriam L Gonzalez; Paula Aristizabal; Adriana Loera-Reyna; Dara Torres; Mario Ornelas-Sánchez; Laura Nuño-Vázquez; Marco Aguilera; Alicia Sánchez; Mitzy Romano; Rebeca Rivera-Gómez; George Relyea; Paola Friedrich; Miguela A Caniza
Journal:  JCO Glob Oncol       Date:  2021-05

5.  Time to antibiotic administration in children with febrile neutropenia: Report from a low middle-income country.

Authors:  Namrata Todurkar; Amita Trehan; Deepak Bansal
Journal:  Indian J Med Res       Date:  2021-04       Impact factor: 5.274

6.  Pediatric patients who receive antibiotics for fever and neutropenia in less than 60 min have decreased intensive care needs.

Authors:  Jennifer L Salstrom; Rebecca L Coughlin; Kathleen Pool; Melissa Bojan; Camille Mediavilla; William Schwent; Michael Rannie; Dawn Law; Michelle Finnerty; Joanne Hilden
Journal:  Pediatr Blood Cancer       Date:  2015-02-07       Impact factor: 3.167

7.  Successful emergency department interventions that reduce time to antibiotics in febrile pediatric cancer patients.

Authors:  Sandra Spencer; MIchele Nypaver; Katherine Hebert; Christopher Benner; Rachel Stanley; Daniel Cohen; Alexander Rogers; Jason Goldstick; Prashant Mahajan
Journal:  BMJ Qual Improv Rep       Date:  2017-03-07

8.  Protocol for a systematic review of time to antibiotics (TTA) in patients with fever and neutropenia during chemotherapy for cancer (FN) and interventions aiming to reduce TTA.

Authors:  Christa Koenig; Jess Morgan; Roland A Ammann; Lillian Sung; Bob Phillips
Journal:  Syst Rev       Date:  2019-04-03

9.  Optimizing Time to Antibiotic Administration in Children with Possible Febrile Neutropenia through Quality Improvement Methodologies.

Authors:  Beech Burns; Melinda Hartenstein; Amber Lin; Denise Langley; Erin Burns; James Heilman; Mary Tanski; Linda Stork; O John Ma
Journal:  Pediatr Qual Saf       Date:  2019-11-21

Review 10.  Optimising Antimicrobial Selection and Duration in the Treatment of Febrile Neutropenia in Children.

Authors:  Jessica E Morgan; Bob Phillips; Gabrielle M Haeusler; Julia C Chisholm
Journal:  Infect Drug Resist       Date:  2021-03-30       Impact factor: 4.003

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