Literature DB >> 21506537

Encapsulation of phthalocyanine supramolecular stacks into virus-like particles.

Melanie Brasch1, Andrés de la Escosura, Yujie Ma, Charlotte Uetrecht, Albert J R Heck, Tomás Torres, Jeroen J L M Cornelissen.   

Abstract

We report herein the encapsulation of a water-soluble phthalocyanine (Pc) into virus-like particles (VLPs) of two different sizes, depending on the conditions. At neutral pH, the cooperative encapsulation/templated assembly of the particles induces the formation of Pc stacks instead of Pc dimers, due to an increased confinement concentration. The Pc-containing VLPs may potentially be used as photosensitizer/vehicle systems for biomedical applications such as photodynamic therapy.
© 2011 American Chemical Society

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Year:  2011        PMID： 21506537     DOI： 10.1021/ja110752u

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  25 in total

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