INTRODUCTION: The purpose of this study is to compare the long-term (≥12 months) angiographic follow-up of aneurysms treated with polymer polyglycolic-lactic acid (PGLA)-coated coils versus bare platinum coils. METHODS: Long-term angiographic follow-up results of 90 aneurysms treated exclusively with PGLA-coated coils were retrospectively analyzed and compared to those of 158 aneurysms treated exclusively with bare platinum coils. RESULTS: There were 32 ruptured aneurysms (35.5%) in the PGLA-coated coil group and 62 (39.2%) in the bare platinum coil group. The mean angiographic follow-up was 29 months in the PGLA-coated coil group versus 27 months in the bare platinum coil group (P = 0.2297). The mean time to angiographic recurrence was 14 months in the PGLA-coated coil group versus 18 months in the bare platinum coil group (P = 0.1088). Recurrence rates were 35.6% (32/90) and 31.0% (49/158) in the PGLA-coated coil and bare platinum coil groups, respectively (P = 0.4837). The major recurrence justifying retreatment was 5.6% (5/90) in the PGLA-coated coil group versus 6.7% (10/158) in the bare platinum coil group (P = 1.000). CONCLUSION: PGLA-coated coils provided no better long-term recanalization rates than bare platinum coils.
INTRODUCTION: The purpose of this study is to compare the long-term (≥12 months) angiographic follow-up of aneurysms treated with polymer polyglycolic-lactic acid (PGLA)-coated coils versus bareplatinum coils. METHODS: Long-term angiographic follow-up results of 90 aneurysms treated exclusively with PGLA-coated coils were retrospectively analyzed and compared to those of 158 aneurysms treated exclusively with bareplatinum coils. RESULTS: There were 32 ruptured aneurysms (35.5%) in the PGLA-coated coil group and 62 (39.2%) in the bareplatinum coil group. The mean angiographic follow-up was 29 months in the PGLA-coated coil group versus 27 months in the bareplatinum coil group (P = 0.2297). The mean time to angiographic recurrence was 14 months in the PGLA-coated coil group versus 18 months in the bareplatinum coil group (P = 0.1088). Recurrence rates were 35.6% (32/90) and 31.0% (49/158) in the PGLA-coated coil and bareplatinum coil groups, respectively (P = 0.4837). The major recurrence justifying retreatment was 5.6% (5/90) in the PGLA-coated coil group versus 6.7% (10/158) in the bareplatinum coil group (P = 1.000). CONCLUSION:PGLA-coated coils provided no better long-term recanalization rates than bareplatinum coils.
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