Literature DB >> 21498594

Cutaneous MCTs: associations with spay/neuter status, breed, body size, and phylogenetic cluster.

Carrie R White1, Ann E Hohenhaus, Jennifer Kelsey, Elizabeth Procter-Gray.   

Abstract

Certain breeds are known to be overrepresented among mast cell tumor (MCT) patients, but other risk factors have not been evaluated. This study presents results from a case-control study of 252 dogs with grade 2 or grade 3 cutaneous MCT. Increased risk for MCT development was found in spayed females (adjusted odds ratio [OR], 4.11), boxers (adjusted OR, 6.09), Labrador retrievers (adjusted OR, 3.95), pugs (adjusted OR, 3.17), golden retrievers (adjusted OR, 2.12), the mastiff and terrier phylogenetic cluster (adjusted OR, 3.19), and breeds classified as large (adjusted OR, 2.10) or giant (adjusted OR, 5.44). Additional studies are needed to evaluate the role of these and other potential risk factors in MCT development.

Entities:  

Mesh:

Year:  2011        PMID: 21498594     DOI: 10.5326/JAAHA-MS-5621

Source DB:  PubMed          Journal:  J Am Anim Hosp Assoc        ISSN: 0587-2871            Impact factor:   1.023


  25 in total

1.  Triplex doppler ultrasonography to describe the uterine arteries during diestrus and progesterone profile in pregnant and non-pregnant bitches of different sizes.

Authors:  J Roos; C Aubanel; Z Niewiadomska; L Lannelongue; C Maenhoudt; A Fontbonne
Journal:  Theriogenology       Date:  2019-09-12       Impact factor: 2.740

2.  Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade.

Authors:  Hiroyuki Mochizuki; Rachael Thomas; Scott Moroff; Matthew Breen
Journal:  Chromosome Res       Date:  2017-01-05       Impact factor: 5.239

3.  Canine mast cell tumours part I: Clinical and survival outcomes.

Authors:  Vanessa S Tamlin; Cynthia D K Bottema; Lucy Woolford; Elizabeth C Dobson; Allan E Kessell; Anne E Peaston
Journal:  Vet Med Sci       Date:  2022-05-03

4.  Aggressive local therapy combined with systemic chemotherapy provides long-term control in grade II stage 2 canine mast cell tumour: 21 cases (1999-2012).

Authors:  A Lejeune; K Skorupski; S Frazier; I Vanhaezebrouck; R B Rebhun; C M Reilly; C O Rodriguez
Journal:  Vet Comp Oncol       Date:  2013-05-31       Impact factor: 2.613

5.  Neutering dogs: effects on joint disorders and cancers in golden retrievers.

Authors:  Gretel Torres de la Riva; Benjamin L Hart; Thomas B Farver; Anita M Oberbauer; Locksley L McV Messam; Neil Willits; Lynette A Hart
Journal:  PLoS One       Date:  2013-02-13       Impact factor: 3.240

6.  Prevalence and risk factors for mast cell tumours in dogs in England.

Authors:  Stephanie Jw Shoop; Stephanie Marlow; David B Church; Kate English; Paul D McGreevy; Anneliese J Stell; Peter C Thomson; Dan G O'Neill; David C Brodbelt
Journal:  Canine Genet Epidemiol       Date:  2015-01-26

7.  Long-term health effects of neutering dogs: comparison of Labrador Retrievers with Golden Retrievers.

Authors:  Benjamin L Hart; Lynette A Hart; Abigail P Thigpen; Neil H Willits
Journal:  PLoS One       Date:  2014-07-14       Impact factor: 3.240

8.  Disorder predispositions and protections of Labrador Retrievers in the UK.

Authors:  Camilla Pegram; Charlotte Woolley; Dave C Brodbelt; David B Church; Dan G O'Neill
Journal:  Sci Rep       Date:  2021-07-14       Impact factor: 4.379

9.  Reproductive capability is associated with lifespan and cause of death in companion dogs.

Authors:  Jessica M Hoffman; Kate E Creevy; Daniel E L Promislow
Journal:  PLoS One       Date:  2013-04-17       Impact factor: 3.240

10.  Concordance of c-kit mutational status in matched primary and metastatic cutaneous canine mast cell tumors at baseline.

Authors:  L Marconato; E Zorzan; M Giantin; S Di Palma; S Cancedda; M Dacasto
Journal:  J Vet Intern Med       Date:  2013-12-26       Impact factor: 3.333

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