Literature DB >> 21497956

[Inappropriate prescription in the community elderly, are we aware of?].

Francisco Mera1, Delia Mestre, Jesús Almeda, Assumpta Ferrer, Francesc Formiga, Sonia Rojas Farreras.   

Abstract

OBJECTIVES: To analyse the prescription according to the STOPP (Screening Tool of Older Person's Prescriptions) and Beer's suitability criteria, and associated factors in patients over 85 years-old. PATIENTS AND METHODS: Cross-sectional study of inappropriate prescribing to over 85 year-olds. The data recorded were: sociodemographic variables, cardiovascular risk factors, chronic illnesses, multiple medication (or polypharmacy) (4 or more) and geriatric assessment. The inappropriate prescription (IP) was evaluated according to total and cardiovascular prescription.
RESULTS: The mean number of drugs in the total of 78 subjects was 6.1 (3.3). Of the total number, 34.6% patients had 1 IP drug; 19.2% had 2; 15.4% had 3 or more, and in total 69.2% of patients had at least one IP drug, and 37.2% had 1 or more IP cardiovascular drugs. The therapeutic groups involved in the overall IP were benzodiazepines (BZP) 23.1%, loop diuretics 17.9%, selective serotonin reuptake inhibitors (SSRIs) 16.7%, and non-steroidal anti-inflammatory drugs (NSAIDs) made up 10.3% of the total criteria. The bivariate analyse found a relationship between the number of drugs and multiple medication (P=.030 in both) and total IP, with no significance found in cardiovascular IP. The multivariate analysis showed an association between multiple medication (OR: 1.22; 95% CI: 1.02-1.47; P=.031) and total IP, and dyslipaemia (OR: 0.30; 95% CI: 0.10-0.87; P=.026) and AHT (OR: 0.15; 95% CI: 0.03-0.78; P=.024) for cardiovascular IP.
CONCLUSIONS: More than half the over 85 year-old patients received an inappropriate prescription. Dyslipaemia and AHT are associated with an inappropriate cardiovascular prescription, and the most frequent drug groups were, BZP, diuretics, SSRIs, and NSAIDs.
Copyright © 2010 SEGG. Published by Elsevier Espana. All rights reserved.

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Year:  2011        PMID: 21497956     DOI: 10.1016/j.regg.2010.12.008

Source DB:  PubMed          Journal:  Rev Esp Geriatr Gerontol        ISSN: 0211-139X


  5 in total

Review 1.  Evaluation of the heterogeneity of studies estimating the association between risk factors and the use of potentially inappropriate drug therapy for the elderly: a systematic review with meta-analysis.

Authors:  Ana Patrícia A L Santos; Daniel Tenório da Silva; Genival Araujo dos Santos Júnior; Carina Carvalho Silvestre; Marco Antônio Prado Nunes; Divaldo Pereira Lyra; Angelo Roberto Antoniolli
Journal:  Eur J Clin Pharmacol       Date:  2015-06-26       Impact factor: 2.953

Review 2.  Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature review.

Authors:  Eline Tommelein; Els Mehuys; Mirko Petrovic; Annemie Somers; Pieter Colin; Koen Boussery
Journal:  Eur J Clin Pharmacol       Date:  2015-09-26       Impact factor: 2.953

3.  [Inappropriate prescribing in polymedicated patients over 64 years-old in primary care].

Authors:  Josefina Filomena Paci; Marta García Alfaro; Francisco Javier Redondo Alonso; María Isabel Fernández San-Martín
Journal:  Aten Primaria       Date:  2014-08-10       Impact factor: 1.137

4.  Prevalence and impact of potentially inappropriate medication on community-dwelling older adults.

Authors:  Alejandra Fernández; Fernando Gómez; Carmen-Lucía Curcio; Edison Pineda; Juliana Fernandes de Souza
Journal:  Biomedica       Date:  2021-03-19       Impact factor: 0.935

5.  [Potentially inappropriate prescribing in older Spanish population according to STOPP/START criteria (STARTREC study)].

Authors:  Inés Cruz-Esteve; Josep Ramón Marsal-Mora; Gisela Galindo-Ortego; Leonardo Galván-Santiago; Marcos Serrano-Godoy; Esther Ribes-Murillo; Jordi Real-Gatius
Journal:  Aten Primaria       Date:  2016-09-29       Impact factor: 1.137

  5 in total

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